The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use 5µl for 106 cells. ab134674-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
FunctionReceptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
Tissue specificityExpressed on monocytes and B-cells, and at lower levels on dendritic cells. Detected at low levels in natural killer (NK) cells.
DomainContains 3 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
Post-translational modificationsPhosphorylated on tyrosine residues. Dephosphorylated by PTPN6.
ab95820 staining LILRB2 in normal Human peripheral blood cells by Flow Cytometry. Cells are co-stained with anti-Human CD14 APC. Cells in the lymphocyte (left) or monocyte (right) gate were used for analysis.
References for Anti-LILRB2 antibody [42D1] (Phycoerythrin) (ab95820)
has not yet been referenced specifically in any publications.
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