Overview

  • Product name
  • Description
    Rabbit polyclonal to LIMS1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Chicken, Zebrafish, Xenopus tropicalis
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-216 of Human LIMS1 (UniProt: P48059).

  • Positive control
    • HeLa, HCT116 and A549 whole cell lysates; Human BT474 xenograft tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab154331 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 37 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Effector of integrin and growth factor signaling, coupling surface receptors to downstream signaling molecules involved in the regulation of cell survival, cell proliferation and cell differentiation. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway.
  • Tissue specificity
    Expressed in most tissues except in the brain.
  • Sequence similarities
    Contains 5 LIM zinc-binding domains.
  • Cellular localization
    Cell junction > focal adhesion. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2310016J22Rik antibody
    • 4921524A02Rik antibody
    • AI507642 antibody
    • AU021743 antibody
    • AW551584 antibody
    • C430041B13Rik antibody
    • LIM and senescent cell antigen like domains 1 antibody
    • LIM and senescent cell antigen-like-containing domain protein 1 antibody
    • LIM zinc finger domain containing 1 antibody
    • LIM-type zinc finger domains 1 antibody
    • Lims1 antibody
    • LIMS1_HUMAN antibody
    • Lims1l antibody
    • Particularly interesting new Cys His protein 1 antibody
    • Particularly interesting new Cys His protein antibody
    • Particularly interesting new Cys-His protein 1 antibody
    • PINCH 1 antibody
    • PINCH antibody
    • PINCH-1 antibody
    • PINCH1 antibody
    • Renal carcinoma antigen NY REN 48 antibody
    • Renal carcinoma antigen NY-REN-48 antibody
    • senescent cell antigen antibody
    • wu:fc32c03 antibody
    • zgc:112533 antibody
    see all

Images

  • Anti-LIMS1 antibody (ab154331) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

    Predicted band size: 37 kDa



    10% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded BT474 xenograft, labeling LIMS1 with ab154331 at 1/100 dilution.

References

ab154331 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab154331.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up