Overview

  • Product nameAnti-LIMS1 antibody [PINCH-C58]
    See all LIMS1 primary antibodies
  • Description
    Mouse monoclonal [PINCH-C58] to LIMS1
  • Tested applicationsSuitable for: WB, IP, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Hamster, Cow, Dog, Human, Monkey
    Predicted to work with: Chicken, Xenopus laevis, Zebrafish
  • Immunogen

    Synthetic peptide:

    CNTKLTLKNKFVEFDMKPV

    conjugated to KLH, corresponding to amino acids 281/299 of Human LIMS1

  • Positive control
    • total cell extract from 293T cells.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab50305 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IP
ELISA
  • Application notesELISA: Use at an assay dependent dilution.
    IP and co-IP: Use at an assay dependent dilution.
    WB: Use at a concentration of 1 - 2 µg/ml. Predicted molecular weight: 37 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionEffector of integrin and growth factor signaling, coupling surface receptors to downstream signaling molecules involved in the regulation of cell survival, cell proliferation and cell differentiation. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway.
    • Tissue specificityExpressed in most tissues except in the brain.
    • Sequence similaritiesContains 5 LIM zinc-binding domains.
    • Cellular localizationCell junction > focal adhesion. Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • 2310016J22Rik antibody
      • 4921524A02Rik antibody
      • AI507642 antibody
      • AU021743 antibody
      • AW551584 antibody
      • C430041B13Rik antibody
      • LIM and senescent cell antigen like domains 1 antibody
      • LIM and senescent cell antigen-like-containing domain protein 1 antibody
      • LIM zinc finger domain containing 1 antibody
      • LIM-type zinc finger domains 1 antibody
      • Lims1 antibody
      • LIMS1_HUMAN antibody
      • Lims1l antibody
      • Particularly interesting new Cys His protein 1 antibody
      • Particularly interesting new Cys His protein antibody
      • Particularly interesting new Cys-His protein 1 antibody
      • PINCH 1 antibody
      • PINCH antibody
      • PINCH-1 antibody
      • PINCH1 antibody
      • Renal carcinoma antigen NY REN 48 antibody
      • Renal carcinoma antigen NY-REN-48 antibody
      • senescent cell antigen antibody
      • wu:fc32c03 antibody
      • zgc:112533 antibody
      see all

    References for Anti-LIMS1 antibody [PINCH-C58] (ab50305)

    This product has been referenced in:
    • Yu L  et al. Selective regulation of p38ß protein and signaling by integrin-linked kinase mediates bladder cancer cell migration. Oncogene N/A:N/A (2013). Read more (PubMed: 23435415) »

    See 1 Publication for this product

    Product Wall

    Thank you for your enquiry. I apologise for the delay in obtaining this information. The laboratory I was trying to contact was having difficulty receiving emails. I can confirm that both these antibodies (ab50305 and ab50298) have been raised again...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"