ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin.
Involvement in disease
Defects in LIPC are the cause of hepatic lipase deficiency (HL deficiency) [MIM:151670].
Belongs to the AB hydrolase superfamily. Lipase family. Contains 1 PLAT domain.
Flow cytometric analysis of K562 cells using ab170642 at a 1/10 dilution (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used.
Immunohistochemical analysis of formalin fixed/ paraffin embedded Human stomach tissue labeling LIPC with ab170642 at a 1/10 dilution, followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot - Anti-LIPC antibody (ab170642)
Anti-LIPC antibody (ab170642) at 1/100 dilution + K562 cell line lysates at 35 µg