Overview

  • Product name
  • Description
    Rabbit polyclonal to LIPC
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WB, Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human LIPC aa 309-338 (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: P11150

  • Positive control
    • K562 cell line lysates. Human stomach tissue. K562 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab170642 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/100 - 1/500. Predicted molecular weight: 56 kDa.
Flow Cyt 1/10 - 1/50.

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

 

Target

  • Function
    Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin.
  • Involvement in disease
    Defects in LIPC are the cause of hepatic lipase deficiency (HL deficiency) [MIM:151670].
  • Sequence similarities
    Belongs to the AB hydrolase superfamily. Lipase family.
    Contains 1 PLAT domain.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • HDLCQ12 antibody
    • Hepatic lipase antibody
    • Hepatic triacylglycerol lipase antibody
    • HL antibody
    • HTGL antibody
    • Lipase member C antibody
    • lipC antibody
    • LIPC_HUMAN antibody
    • LIPH antibody
    see all

Images

  • Flow cytometric analysis of K562 cells using ab170642 at a 1/10 dilution (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used.

  • Immunohistochemical analysis of formalin fixed/ paraffin embedded Human stomach tissue labeling LIPC with ab170642 at a 1/10 dilution, followed by peroxidase conjugation of the secondary antibody and DAB staining.

  • Anti-LIPC antibody (ab170642) at 1/100 dilution + K562 cell line lysates at 35 µg

    Predicted band size: 56 kDa

References

ab170642 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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