Overview

  • Product name
    Anti-LIPC antibody - N-terminal
    See all LIPC primary antibodies
  • Description
    Rabbit polyclonal to LIPC - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human LIPC aa 16-44 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: P11150

  • Positive control
    • CEM cell line lysate; CEM cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab170338 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 56 kDa.
Flow Cyt 1/10 - 1/50.

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

 

Target

  • Function
    Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin.
  • Involvement in disease
    Defects in LIPC are the cause of hepatic lipase deficiency (HL deficiency) [MIM:151670].
  • Sequence similarities
    Belongs to the AB hydrolase superfamily. Lipase family.
    Contains 1 PLAT domain.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • HDLCQ12 antibody
    • Hepatic lipase antibody
    • Hepatic triacylglycerol lipase antibody
    • HL antibody
    • HTGL antibody
    • Lipase member C antibody
    • lipC antibody
    • LIPC_HUMAN antibody
    • LIPH antibody
    see all

Images

  • Anti-LIPC antibody - N-terminal (ab170338) at 1/100 dilution + CEM cell line lysate at 35 µg

    Predicted band size: 56 kDa

  • Flow cytometric analysis of CEM cells labeling LIPC with ab170338 at 1/10 dilution (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

References

ab170338 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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