• Product name
  • Description
    Mouse polyclonal to LIPH
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length Human LIPH (NP_640341, 1 a.a. - 451 a.a)

  • Positive control
    • Human pancreas tissue lysate. LIPH transfected 293T cell lysate.



Our Abpromise guarantee covers the use of ab88768 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 51 kDa.


  • Function
    Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG).
  • Tissue specificity
    Present in intestine (at protein level). Expressed in colon, prostate, kidney, pancreas, ovary, testis, intestine, lung and pancreas. Expressed at lower level in brain, spleen and heart. In hair, it is prominently expressed in hair follicles, including the stem cell-rich bulge region.
  • Involvement in disease
    Defects in LIPH are the cause of hypotrichosis localized autosomal recessive type 2 (LAH2) [MIM:604379]; also known as alopecia universalis congenita Mari type. A condition characterized by the presence of less than the normal amount of hair. Affected individuals have sparse or absent scalp, axillary and body hair and sparse eyebrows and eyelashes.
    Defects in LIPH are the cause of woolly hair autosomal recessive type 2 (ARWH2) [MIM:604379]. A hair shaft disorder characterized by fine and tightly curled hair. Compared to normal curly hair that is observed in some populations, woolly hair grows slowly and stops growing after a few inches. Under light microscopy, woolly hair shows some structural anomalies, including trichorrexis nodosa and tapered ends. Some individuals may present with hypotrichosis.
  • Sequence similarities
    Belongs to the AB hydrolase superfamily. Lipase family.
  • Cellular localization
    Secreted. Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • AH antibody
    • ARWH2 antibody
    • LAH2 antibody
    • Lipase H antibody
    • Lipase member H antibody
    • LIPH antibody
    • LIPH_HUMAN antibody
    • LPD lipase related protein antibody
    • LPD lipase-related protein antibody
    • LPDLR antibody
    • Membrane associated phosphatidic acid selective phospholipase A1 alpha antibody
    • Membrane bound phosphatidic acid selective phospholipase A1 antibody
    • Membrane-associated phosphatidic acid-selective phospholipase A1-alpha antibody
    • mPA PLA1 antibody
    • mPA-PLA1 alpha antibody
    • MPAPLA1 antibody
    • OTTHUMP00000210343 antibody
    • OTTHUMP00000210344 antibody
    • Phospholipase A1 member B antibody
    • PLA1B antibody
    see all


  • Anti-LIPH antibody (ab88768) at 1 µg/ml + Human pancreas lysate at 50 µg

    Predicted band size : 51 kDa
    Observed band size : 51 kDa
  • All lanes : Anti-LIPH antibody (ab88768) at 1 µg/ml

    Lane 1 : LIPH transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Predicted band size : 51 kDa
    Observed band size : 60 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 34 kDa. We are unsure as to the identity of these extra bands.


ab88768 has not yet been referenced specifically in any publications.

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