Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab115476 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/64000.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionRegulates fatty acid metabolism. Magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis.
  • Tissue specificitySignificant expression in intestine and other regions of the gastrointestinal tract.
  • Sequence similaritiesBelongs to the lipin family.
  • DomainContains 1 Asp-Xaa-Asp-Xaa-Thr (DXDXT) motif, a catalytic motif known to be essential for phosphatidate phosphatase activity.
    Contains one Leu-Xaa-Xaa-Ile-Leu (LXXIL) motif, a motif known to be a transcriptional binding motif.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • dJ450M14.2 antibody
    • dJ450M14.3 antibody
    • dJ620E11.2 antibody
    • Lipin 3 like antibody
    • Lipin-3 antibody
    • Lipin-3-like antibody
    • Lipin3 antibody
    • LIPN3L antibody
    • LPIN 3 antibody
    • Lpin3 antibody
    • LPIN3_HUMAN antibody
    • Phosphatidate phosphatase LPIN3 antibody
    • RP4 620E11.3 antibody
    • SMP2 antibody
    see all

Anti-Lipin 3 antibody images

  • ab115476, at 2.5µg/ml staining Lipin 3 in formalin-fixed, paraffin-embedded Human thyroid tissue by Immunohistochemistry, using a biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References for Anti-Lipin 3 antibody (ab115476)

ab115476 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"