Overview

  • Product name
  • Description
    Goat polyclonal to Lipin 3
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Orangutan
  • Immunogen

    Synthetic peptide:

    C-KPKQKEDAVATD

    , corresponding to internal sequence amino acids 149-160 of Human Lipin 3

  • Positive control
    • Human liver lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab53548 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 2 - 3 µg/ml.

Target

  • Function
    Regulates fatty acid metabolism. Magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis.
  • Tissue specificity
    Significant expression in intestine and other regions of the gastrointestinal tract.
  • Sequence similarities
    Belongs to the lipin family.
  • Domain
    Contains 1 Asp-Xaa-Asp-Xaa-Thr (DXDXT) motif, a catalytic motif known to be essential for phosphatidate phosphatase activity.
    Contains one Leu-Xaa-Xaa-Ile-Leu (LXXIL) motif, a motif known to be a transcriptional binding motif.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • dJ450M14.2 antibody
    • dJ450M14.3 antibody
    • dJ620E11.2 antibody
    • Lipin 3 like antibody
    • Lipin-3 antibody
    • Lipin-3-like antibody
    • Lipin3 antibody
    • LIPN3L antibody
    • LPIN 3 antibody
    • Lpin3 antibody
    • LPIN3_HUMAN antibody
    • Phosphatidate phosphatase LPIN3 antibody
    • RP4 620E11.3 antibody
    • SMP2 antibody
    see all

Images

  • ab53548 at 2.5µg/ml staining Lipin 3 in human thyroid gland tissue section by Immunohistochemistry (Formalin/ PFA-fixed paraffin-embedded tissue sections). The tissue underwent antigen retrieval by steam in citrate buffer pH 6.0. The AP staining procedure was used for detection.

References

ab53548 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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