Overview

  • Product name
    Anti-Liprin alpha 2 antibody
    See all Liprin alpha 2 primary antibodies
  • Description
    Rabbit polyclonal to Liprin alpha 2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 121-416 of Human Liprin alpha 2 (Uniprot: O75334)

  • Positive control
    • Mouse brain lysate
  • General notes
    Keep as a concentrated solution

Properties

Applications

Our Abpromise guarantee covers the use of ab155411 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/5000 - 1/20000. Predicted molecular weight: 143 kDa.

Target

  • Function
    Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.
  • Tissue specificity
    Expressed only in brain.
  • Sequence similarities
    Belongs to the liprin family. Liprin-alpha subfamily.
    Contains 3 SAM (sterile alpha motif) domains.
  • Domain
    The N-terminal coiled coil regions mediate homodimerization preferentially and heterodimerization type alpha/alpha. The C-terminal, non-coiled coil regions mediate heterodimerization type alpha/beta and interaction with PTPRD, PTPRF and PTPRS.
  • Cellular localization
    Cytoplasm. Cell surface. Colocalizes with PTPRF at the cell surface.
  • Information by UniProt
  • Database links
  • Alternative names
    • LIPA2_HUMAN antibody
    • Liprin-alpha-2 antibody
    • PPFIA2 antibody
    • Protein tyrosine phosphatase receptor type f polypeptide interacting protein alpha 2 antibody
    • Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2 antibody
    • Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 antibody
    • PTPRF interacting protein alpha 2 antibody
    • PTPRF-interacting protein alpha-2 antibody
    see all

Images

  • Anti-Liprin alpha 2 antibody (ab155411) at 1/10000 dilution + Mouse brain whole cell lysate at 20 µg

    Predicted band size : 143 kDa

References

ab155411 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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