• Product nameAnti-LMAN1 antibody
    See all LMAN1 primary antibodies
  • Description
    Rabbit polyclonal to LMAN1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    KLH conjugated synthetic peptide selected from the center of Human LMAN1.

  • Positive control
    • NCI-H460 or NIH-3T3 cell line lysates


  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesThis antibody is purified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab93177 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesWB: 1/100 - 1/500. Predicted molecular weight: 57 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins.
    • Tissue specificityUbiquitous.
    • Involvement in diseaseDefects in LMAN1 are THE cause of factor V and factor VIII combined deficiency type 1 (F5F8D1) [MIM:227300]; also known as multiple coagulation factor deficiency I (MCFD1). F5F8D1 is an autosomal recessive blood coagulation disorder characterized by bleeding symptoms similar to those in hemophilia or parahemophilia, that are caused by single deficiency of FV or FVIII, respectively. The most common symptoms are epistaxis, menorrhagia, and excessive bleeding during or after trauma. Plasma levels of coagulation factors V and VIII are in the range of 5 to 30% of normal.
    • Sequence similaritiesContains 1 L-type lectin-like domain.
    • Post-translational
      The N-terminal may be partly blocked.
    • Cellular localizationEndoplasmic reticulum-Golgi intermediate compartment membrane. Golgi apparatus membrane. Endoplasmic reticulum membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Endoplasmic reticulum golgi intermediate compartment protein 53 antibody
      • ER-Golgi intermediate compartment 53 kDa protein antibody
      • ERGIC-53 antibody
      • ERGIC53 antibody
      • ERGIC53 like protein antibody
      • F5F8D antibody
      • FMFD1 antibody
      • Gp58 antibody
      • Intracellular mannose specific lectin antibody
      • Intracellular mannose-specific lectin MR60 antibody
      • Lectin mannose binding 1 antibody
      • Lectin mannose-binding 1 antibody
      • Lman1 antibody
      • LMAN1 like protein antibody
      • LMAN1_HUMAN antibody
      • MCFD1 antibody
      • MR60 antibody
      • Protein ERGIC-53 antibody
      see all

    Anti-LMAN1 antibody images

    • Anti-LMAN1 antibody (ab93177) at 1/100 dilution + NCI-H460 cell line lysates at 35 µg

      Predicted band size : 57 kDa
    • Anti-LMAN1 antibody (ab93177) at 1/100 dilution + NIH-3T3 cell line lysates at 35 µg

      Predicted band size : 57 kDa

    References for Anti-LMAN1 antibody (ab93177)

    This product has been referenced in:
    • Li Q  et al. Estradiol accelerates the effects of fluoxetine on serotonin 1A receptor signaling. Psychoneuroendocrinology 38:1145-57 (2013). WB ; Rat . Read more (PubMed: 23219224) »

    See 1 Publication for this product

    Product Wall

    Abcam has not validated the combination of species/application used in this Abreview.
    Application Immunocytochemistry/ Immunofluorescence
    Sample Mouse Cell (B16)
    Specification B16
    Fixative Paraformaldehyde
    Permeabilization Yes - PBS/ BSA 0.2%/ SAPONIN 0.05%
    Blocking step BSA as blocking agent for 16 hour(s) and 0 minute(s) · Concentration: 0.2% · Temperature: 4°C

    Ms. Alice Rochard

    Verified customer

    Submitted Jan 17 2013

    Merci de nous avoir contactés.

    Oui tout à fait. Vous pouvez utilisez ce code pour l’achat d’un autre anticorps différent que celui déjà testé pour lequel vous nous avez soumis vos ré...

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