Overview

  • Product nameAnti-LMO2 antibody [1A9-1]
    See all LMO2 primary antibodies
  • Description
    Mouse monoclonal [1A9-1] to LMO2
  • Tested applicationsSuitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Purified proprietary LMO2 fusion protein

  • Positive control
    • WB: Raji cell lysates; IHC-P: Human tonsil tissue.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone number1A9-1
  • IsotypeIgG1
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab80046 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 18 kDa.
IHC-P Use at an assay dependent concentration. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC/IF Use at an assay dependent concentration.

Target

  • FunctionActs with TAL1/SCL to regulate red blood cell development. Also acts with LDB1 to maintain erythroid precursors in an immature state.
  • Involvement in diseaseNote=A chromosomal aberration involving LMO2 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(11,14)(p13;q11) with TCRD.
  • Sequence similaritiesContains 2 LIM zinc-binding domains.
  • DomainThe second LIM zinc-binding domain interacts with KDM5A.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cysteine rich protein TTG 2 antibody
    • Cysteine rich protein TTG2 antibody
    • Cysteine-rich protein TTG-2 antibody
    • LIM domain only 2 (rhombotin like 1) antibody
    • LIM domain only 2 antibody
    • LIM domain only protein 2 antibody
    • LMO 2 antibody
    • LMO-2 antibody
    • lmo2 antibody
    • RBTN 2 antibody
    • RBTN L1 antibody
    • RBTN2 antibody
    • RBTN2_HUMAN antibody
    • RBTNL 1 antibody
    • RBTNL1 antibody
    • RHOM 2 antibody
    • RHOM2 antibody
    • Rhombotin 2 antibody
    • Rhombotin like 1 antibody
    • Rhombotin-2 antibody
    • Rhombotin2 antibody
    • T cell translocation gene 2 antibody
    • T cell translocation protein 2 antibody
    • T-cell translocation protein 2 antibody
    • TTG 2 antibody
    • TTG2 antibody
    see all

References for Anti-LMO2 antibody [1A9-1] (ab80046)

This product has been referenced in:
  • Natkunam Y  et al. The oncoprotein LMO2 is expressed in normal germinal-center B cells and in human B-cell lymphomas. Blood 109:1636-42 (2007). WB, IHC-P ; Human . Read more (PubMed: 17038524) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"