Overview

  • Product name
  • Description
    Rabbit polyclonal to LMX1b
  • Specificity
    ab70174 detects endogenous levels of total LMX1b protein.
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide: DLLSSVSPDE SDSVKSEDED GDMKPAKGQG , corresponding to internal sequence amino acids 151-180 of Human LMX1b

  • Positive control
    • Jurkat, 293 and HUVEC cell extracts.

Properties

Applications

Our Abpromise guarantee covers the use of ab70174 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 41 kDa (predicted molecular weight: 41 kDa).
ELISA 1/40000.

Target

  • Function
    Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels.
  • Tissue specificity
    Expressed in most tissues. Highest levels in testis, thyroid, duodenum, skeletal muscle, and pancreatic islets.
  • Involvement in disease
    Defects in LMX1B are the cause of nail-patella syndrome (NPS) [MIM:161200]; also known as onychoosteodysplasia. NPS is a disease that cause abnormal skeletal patterning and renal dysplasia.
  • Sequence similarities
    Contains 1 homeobox DNA-binding domain.
    Contains 2 LIM zinc-binding domains.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • LIM homeo box transcription factor 1 beta antibody
    • LIM homeobox transcription factor 1 beta antibody
    • LIM homeobox transcription factor 1-beta antibody
    • LIM-homeobox protein 1.2 antibody
    • LIM/homeobox protein 1.2 antibody
    • LIM/homeobox protein LMX1B antibody
    • LMX 1.2 antibody
    • LMX-1.2 antibody
    • LMX1.2 antibody
    • LMX1B antibody
    • LMX1B_HUMAN antibody
    • MGC138325 antibody
    • MGC142051 antibody
    • NPS 1 antibody
    • NPS1 antibody
    see all

Anti-LMX1b antibody images

  • All lanes : Anti-LMX1b antibody (ab70174) at 1/500 dilution

    Lane 1 : Jurkat cell extracts
    Lane 2 : 293 cell extracts
    Lane 3 : HUVEC cell extracts
    Lane 4 : 293 cell extracts with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 41 kDa
    Observed band size : 41 kDa

References for Anti-LMX1b antibody (ab70174)

ab70174 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab70174.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up