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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
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Immunogen affinity purified
ab70174 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||1/500 - 1/1000. Detects a band of approximately 41 kDa (predicted molecular weight: 41 kDa).
Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels.
Expressed in most tissues. Highest levels in testis, thyroid, duodenum, skeletal muscle, and pancreatic islets.
Involvement in disease
Defects in LMX1B are the cause of nail-patella syndrome (NPS) [MIM:161200]; also known as onychoosteodysplasia. NPS is a disease that cause abnormal skeletal patterning and renal dysplasia.
Contains 1 homeobox DNA-binding domain.
Contains 2 LIM zinc-binding domains.
Information by UniProt
- LIM homeo box transcription factor 1 beta antibody
- LIM homeobox transcription factor 1 beta antibody
- LIM homeobox transcription factor 1-beta antibody
Anti-LMX1b antibody images
References for Anti-LMX1b antibody (ab70174)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"