Overview

  • Product nameAnti-LOX antibody
    See all LOX primary antibodies
  • Description
    Rabbit polyclonal to LOX
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide selected from the Center region of Human LOX conjugated to KLH (NP_002308.2).

  • Positive control
    • MDA-MB468 cell line lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab94991 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 47 kDa.

Target

  • FunctionResponsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. In addition to cross-linking of extracellular matrix proteins, may have a direct role in tumor suppression.
  • Tissue specificityHeart, placenta, skeletal muscle, kidney, lung and pancreas.
  • Involvement in diseaseDefects in LOX may be a cause of cutis laxa autosomal recessive type 1 (ARCL1) [MIM:219100].
  • Sequence similaritiesBelongs to the lysyl oxidase family.
  • Post-translational
    modifications
    The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
  • Cellular localizationSecreted > extracellular space.
  • Information by UniProt
  • Database links
  • Alternative names
    • lox antibody
    • LYOX antibody
    • LYOX_HUMAN antibody
    • Lysyl oxidase antibody
    • MGC105112 antibody
    • Protein lysine 6 oxidase antibody
    • Protein-lysine 6-oxidase antibody
    see all

Anti-LOX antibody images

  • Anti-LOX antibody (ab94991) at 1/100 dilution + MDA-MB468 cell line lysates at 35 µg

    Predicted band size : 47 kDa

References for Anti-LOX antibody (ab94991)

ab94991 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab94991.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"