Overview

  • Product nameAnti-LOXHD1 antibody
  • Description
    Rabbit polyclonal to LOXHD1
  • Tested applicationsSuitable for: IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: GNGGETRENV WLILEGRKNR SKEFLMENSS RQRAFRKGTT DTFEFDSIYL GDIASLCVGH LAREDRFIPK RELVWHVKTI TITEMEYGNV, corresponding to internal sequence amino acids 1747-1836 of Human LOXHD1.

  • Positive control
    • Human smooth muscle tissue; Human Plasma lysate.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle. Store undiluted.
  • Storage bufferpH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab122824 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

Target

  • FunctionInvolved in hearing. Required for normal function of hair cells in the inner ear.
  • Involvement in diseaseDefects in LOXHD1 are the cause of deafness autosomal recessive type 77 (DFNB77) [MIM:613079]. A form of non-syndromic deafness characterized by preserved low-frequency hearing, and a trend toward mild to moderate mid-frequency and high-frequency hearing loss during childhood and adolescence. Hearing loss progresses to become moderate to severe at mid and high frequencies during adulthood.
  • Sequence similaritiesContains 14 PLAT domains.
  • Cellular localizationCell projection > stereocilium.
  • Information by UniProt
  • Database links
  • Alternative names
    • DFNB77 antibody
    • FLJ32670 antibody
    • LH2D1 antibody
    • Lipoxygenase homology domain-containing protein 1 antibody
    • Lipoxygenase homology domains 1 antibody
    • LOXH1_HUMAN antibody
    • LOXHD1 antibody
    see all

Anti-LOXHD1 antibody images

  • Immunofluorescent staining of Human cell line U-251 MG shows positivity in nucleus but not nucleoli. Recommended concentration of ab122824 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab122824 at 1/50 dilution staining LOXHD1 in Paraffin-embedded Human smooth muscle tissue by Immunohistochemistry.

References for Anti-LOXHD1 antibody (ab122824)

ab122824 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"