Overview

  • Product name
  • Description
    Rabbit polyclonal to LPCAT1
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to internal sequence amino acids of Human LPCAT1.

  • Positive control
    • Human Brain cerebellum tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -80°C.
  • Storage buffer
    Preservative: 0.1% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Polyclonal
  • Isotype
    IgG

Applications

Our Abpromise guarantee covers the use of ab115458 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 µg/ml. Antigen retrieval with HIER and sodium citrate at pH 6.0 is required.

Target

  • Function
    Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-independent. Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively. May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology.
  • Pathway
    Lipid metabolism; phospholipid metabolism.
  • Sequence similarities
    Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
    Contains 2 EF-hand domains.
  • Domain
    The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphocholine.
    The di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins.
  • Cellular localization
    Endoplasmic reticulum membrane. Golgi apparatus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1 acylglycerophosphocholine O acyltransferase antibody
    • 1 alkylglycerophosphocholine O acetyltransferase antibody
    • 1-acylglycerophosphocholine O-acyltransferase antibody
    • 1-alkylglycerophosphocholine O-acetyltransferase antibody
    • Acetyl CoA:lyso PAF acetyltransferase antibody
    • Acetyl CoA:lyso platelet activating factor acetyltransferase antibody
    • Acetyl-CoA:lyso-PAF acetyltransferase antibody
    • Acetyl-CoA:lyso-platelet-activating factor acetyltransferase antibody
    • Acyl CoA:lysophosphatidylcholine acyltransferase 1 antibody
    • Acyltransferase like 2 antibody
    • Acyltransferase-like 2 antibody
    • AGPAT10 antibody
    • AGPAT9 antibody
    • AYTL1 antibody
    • AYTL2 antibody
    • FLJ12443 antibody
    • FLJ41609 antibody
    • LPC acyltransferase 1 antibody
    • LPC acyltransferase antibody
    • lpcat antibody
    • LPCAT-1 antibody
    • LPCAT1 antibody
    • Lyso PAF acetyltransferase antibody
    • Lyso-PAF acetyltransferase antibody
    • LysoPAFAT antibody
    • LysoPC acyltransferase 1 antibody
    • Lysophosphatidylcholine acyltransferase 1 antibody
    • PCAT1_HUMAN antibody
    • PFAAP3 antibody
    • Phosphonoformate immuno associated protein 3 antibody
    • Phosphonoformate immuno-associated protein 3 antibody
    see all

Images

  • ab115458 at 10 µg/ml staining Formalin-fixed, Paraffin-embedded LPCAT1 in Human Brain cerebellum tissue by Immunohistochemistry.

References

ab115458 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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