For the best experience on the Abcam website please upgrade to a modern browser such as
Product name Anti-LRFN1 antibody
Rabbit polyclonal to LRFN1
Tested applications Suitable for:
ICC/IF, WB, IHC-P more details
Mouse, Rat, Human
18 amino acid peptide near the C terminus of Human LRFN1 (Q9P244).
Human brain lysate, Mouse brain tissue
Storage instructions Shipped at 4°C. Store at 4°C (stable for up to 12 months).
Storage buffer Preservative: 0.02% Sodium Azide
Concentration information loading...
Purity Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 20 µg/ml.
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 82 kDa.
Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol.
Function Promotes neurite outgrowth in hippocampal neurons. Involved in the regulation and maintenance of excitatory synapses. Induces the clustering of excitatory postsynaptic proteins, including DLG4, DLGAP1, GRIA1 and GRIN1.
Sequence similarities Belongs to the LRFN family. Contains 1 fibronectin type-III domain. Contains 1 Ig-like (immunoglobulin-like) domain. Contains 7 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain.
Domain The PDZ-binding motif is required for neurite outgrowth promotion and for DLG1-, DLG3- and DLG4-binding.
Post-translational modifications Glycosylated.
Cellular localization Membrane. Cell junction, synapse. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Detected in excitatory, but not inhibitory, synaptic plasma membrane.
Information by UniProt
Leucine rich repeat and fibronectin type III domain containing 1 antibody
Leucine rich repeat and fibronectin type III domain containing protein 1 antibody
Anti-LRFN1 antibody images
Immunocytochemistry/ Immunofluorescence - Anti-LRFN1 antibody (ab106365)
Immunofluorescence of LRFN1 in mouse brain tissue with ab106365 at 20 ug/mL.
Western blot - LRFN1 antibody (ab106365)
Lane 1 : Anti-LRFN1 antibody (ab106365) at 1 µg/ml Lane 2 : Anti-LRFN1 antibody (ab106365) at 2 µg/ml Lane 1 : Human brain lysate Lane 2 : Human brain lysate Lysates/proteins at 15 µg per lane. Predicted band size : 82 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - LRFN1 antibody (ab106365)
ab106365 at 2.5 µg/ml staining LRFN1 in Mouse brain tissue by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.
References for Anti-LRFN1 antibody (ab106365)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"