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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer Preservative: None
Constituents: 1X PBS, pH 7.2
Concentration information loading...
Purity Protein G purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 78 kDa (predicted molecular weight: 82 kDa).
Function Promotes neurite outgrowth in hippocampal neurons. Involved in the regulation and maintenance of excitatory synapses. Induces the clustering of excitatory postsynaptic proteins, including DLG4, DLGAP1, GRIA1 and GRIN1.
Sequence similarities Belongs to the LRFN family. Contains 1 fibronectin type-III domain. Contains 1 Ig-like (immunoglobulin-like) domain. Contains 7 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain.
Domain The PDZ-binding motif is required for neurite outgrowth promotion and for DLG1-, DLG3- and DLG4-binding.
Post-translational modifications Glycosylated.
Cellular localization Membrane. Cell junction, synapse. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Detected in excitatory, but not inhibitory, synaptic plasma membrane.
Information by UniProt
Leucine rich repeat and fibronectin type III domain containing 1 antibody
Leucine rich repeat and fibronectin type III domain containing protein 1 antibody
Anti-LRFN1 antibody images
References for Anti-LRFN1 antibody (ab69662)
has not yet been referenced specifically in any publications.
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