Anti-LRP12 antibody - C-terminal (ab170501)

Overview

  • Product name
    Anti-LRP12 antibody - C-terminal
    See all LRP12 primary antibodies
  • Description
    Rabbit polyclonal to LRP12 - C-terminal
  • Tested applications
    Suitable for: Flow Cyt, ICC/IF, IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human LRP12 aa 642-671 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q9Y561

  • Positive control
    • Jurkat cell line lysate, Human skeletal muscle tissue, U-251MG cells, Jurkat cells

Properties

Applications

Our Abpromise guarantee covers the use of ab170501 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/10 - 1/50. ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
ICC/IF 1/10 - 1/50.
IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/100 - 1/500. Predicted molecular weight: 94 kDa.

Target

  • Function
    Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor.
  • Tissue specificity
    Widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas, but not in tissues consisting of a large number of epithelial cells, such as liver and kidney. Expressed at very low levels in a number of tumor-derived cell lines.
  • Sequence similarities
    Belongs to the LDLR family.
    Contains 2 CUB domains.
    Contains 5 LDL-receptor class A domains.
  • Cellular localization
    Membrane. Membrane, coated pit.
  • Information by UniProt
  • Database links
  • Alternative names
    • AI848829 antibody
    • FLJ12929 antibody
    • Low density lipoprotein receptor related protein 12 antibody
    • Low-density lipoprotein receptor-related protein 12 antibody
    • LRP 12 antibody
    • LRP-12 antibody
    • LRP12 antibody
    • LRP12_HUMAN antibody
    • ST7 antibody
    • Suppressor of tumorigenicity 7 protein antibody
    see all

Images

  • Flow Cytometrical analysis of Jurkat cells with ab170501 antibody at a dilution of 1/10 (right histogram) compared to a negative control cell (left histogram).

  • Immunofluorescent analysis of U-251MG cells labeling LRP12 with ab170501 at 1/10 followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green) and DAPI staining.

  • Immunohistochemical analysis of paraffin embedded Human skeletal muscle tissue labeling LRP12 with ab170501 at 1/10.

  • Anti-LRP12 antibody - C-terminal (ab170501) at 1/100 dilution + Jurkat cell line lysate at 35 µg

    Predicted band size : 94 kDa

References

ab170501 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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