Overview

  • Product name
    Anti-LRP3 antibody
  • Description
    Rabbit polyclonal to LRP3
  • Tested applications
    Suitable for: IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Monkey
  • Immunogen

    Synthetic peptide corresponding to Human LRP3 aa 676-693 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH).
    Sequence:

    EVGPSGPPLPSGLRDPEC

  • Positive control
    • Human skin tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 0.1% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab115197 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ELISA 1/1000.

Target

  • Function
    Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.
  • Tissue specificity
    Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte.
  • Sequence similarities
    Belongs to the LDLR family.
    Contains 2 CUB domains.
    Contains 4 LDL-receptor class A domains.
  • Cellular localization
    Membrane. Membrane > coated pit.
  • Information by UniProt
  • Database links
  • Alternative names
    • 105 kDa low-density lipoprotein receptor-related protein antibody
    • CTD-2540B15.13 antibody
    • hLRp105 antibody
    • Low density lipoprotein receptor related protein 3 antibody
    • Low-density lipoprotein receptor-related protein 3 antibody
    • LRP-3 antibody
    • Lrp3 antibody
    • LRP3_HUMAN antibody
    see all

Anti-LRP3 antibody images

  • Immunohistochemistry Image of Human Skin (formalin-fixed, paraffin-embedded) stained with LRP3 antibody (ab115197) at 10 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References for Anti-LRP3 antibody (ab115197)

ab115197 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab115197.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up