Overview

  • Product nameAnti-LRRC6 antibody
    See all LRRC6 primary antibodies
  • Description
    Rabbit polyclonal to LRRC6
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Horse, Guinea pig, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 71-120 (LNLALNNIEK IENLEGCEEL AKLDLTVNFI GELSSIKNLQ HNIHLKELFL) of Human LRRC6 (NP_036604).

  • Positive control
    • PANC1 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab98167 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 54 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionMay play a role in dynein arm assembly, hence essential for proper axoneme building for cilia motility.
  • Tissue specificityExpressed predominantly in testis and in nasal epithelial cells.
  • Involvement in diseaseDefects in LRRC6 are the cause of primary ciliary dyskinesia 19 (CILD19) [MIM:614935]. A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.
  • Sequence similaritiesBelongs to the tilb protein family.
    Contains 1 CS domain.
    Contains 4 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
  • Cellular localizationCytoplasm. Cell projection > cilium.
  • Information by UniProt
  • Database links
  • Alternative names
    • Leucine rich repeat containing 6 antibody
    • Leucine rich repeat containing protein 6 antibody
    • Leucine rich testis specific protein antibody
    • Leucine-rich repeat-containing protein 6 antibody
    • Leucine-rich testis-specific protein antibody
    • Lrrc6 antibody
    • LRTP antibody
    • Protein TILB homolog antibody
    • Testis specific leucine rich repeat protein antibody
    • Testis-specific leucine-rich repeat protein antibody
    • TILB_HUMAN antibody
    • TSLRP antibody
    see all

Anti-LRRC6 antibody images

  • Anti-LRRC6 antibody (ab98167) at 1 µg/ml (in 5% skim milk / PBS buffer) + PANC1 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 54 kDa

References for Anti-LRRC6 antibody (ab98167)

ab98167 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab98167.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"