FunctionTranscriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA.
Tissue specificityUbiquitously expressed.
Sequence similaritiesBelongs to the LRRFIP family.
Developmental stageWidely expressed in fetal tissues.