Overview

  • Product name
  • Description
    Rabbit polyclonal to LRRTM1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Rat, Cow, Dog, Human, Pig, Macaque monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 450 to the C-terminus of Human LRRTM1.

  • Positive control
    • This antibody gave a positive signal in the following tissue lysates: Mouse Forebrain; Mouse Hippocampus; Mouse Brain P0; Mouse Olfactory Bulb.

Properties

Applications

Our Abpromise guarantee covers the use of ab106414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/250. Detects a band of approximately 65 kDa (predicted molecular weight: 59 kDa).

Target

  • Function
    May play a role during the development of specific forebrain structures by influencing neuronal differentiation and connectivity, with a possible role in intracellular trafficking within axons.
  • Tissue specificity
    Predominantly expression in forebrain regions including thalamus and cerebral cortex.
  • Sequence similarities
    Belongs to the LRRTM family.
    Contains 9 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
  • Cellular localization
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 4632401D06Rik antibody
    • AW125451 antibody
    • FLJ32082 antibody
    • Leucine rich repeat transmembrane neuronal 1 antibody
    • Leucine rich repeat transmembrane neuronal 1 protein antibody
    • Leucine-rich repeat transmembrane neuronal protein 1 antibody
    • LRRT1_HUMAN antibody
    • LRRTM1 antibody
    • Lrrtm1 leucine rich repeat transmembrane neuronal 1 antibody
    • OTTHUMP00000194829 antibody
    see all

Images

  • All lanes : Anti-LRRTM1 antibody (ab106414) at 1/250 dilution

    Lane 1 : Forebrain (Mouse) Tissue Lysate
    Lane 2 : Mouse Hippocampus Tissue Lysate
    Lane 3 : Mouse brain tissue lysate - total protein (0 days) (ab7188)
    Lane 4 : Mouse Olfactory Bulb Lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 59 kDa
    Observed band size : 65 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 130 kDa,30 kDa,40 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 8 minutes

References

ab106414 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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