The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 20 µg/ml.
Use a concentration of 2.5 µg/ml.
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 59 kDa.
Use at an assay dependent concentration.
FunctionInvolved in the development and maintenance of excitatory synapse in the vertebrate nervous system. Regulates surface expression of AMPA receptors. Acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B.
Tissue specificityExpressed in neuronal tissues.
Sequence similaritiesBelongs to the LRRTM family. Contains 10 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain.
DomainSynaptogenic effects are mediated by the extracellular LRR region.