Overview

  • Product name
  • Description
    Goat polyclonal to LSP1
  • Specificity
    ab112887 is expected to recognize both reported isoforms (NP_002330.1; NP_001013271.1). Reported variants represent identical protein: NP_001013273.1, NP_001013271.1, NP_001013272.1.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
    Predicted to work with: Cow, Dog, Baboon
  • Immunogen

    Synthetic peptide:

    RYKFVATGHGKYEKV

    by a Cysteine residue linker, corresponding to C terminal amino acids 317-331 of Human LSP1 isoform 1 (NP_002330.1) and amino acids 255-269 of Human LSP1 isoform 2 (NP_001013271.1).

  • Positive control
    • Human, Mouse and Rat Liver, Human Lymph Node, Tonsil and Peripheral Blood Mononucleocytes lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 99% Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab112887 was purified from Goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab112887 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.05 - 0.2 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 37 kDa). For 1 hour.

Target

  • Function
    May play a role in mediating neutrophil activation and chemotaxis.
  • Tissue specificity
    Activated T-lymphocytes.
  • Post-translational
    modifications
    Phosphorylated by casein kinase II, protein kinase C and MAPKAPK2. Phosphorylation by PKC induces translocation from membrane to cytoplasm. Phosphorylation by MAPKAPK2 may regulate neutrophil chemotaxis.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 47 kDa actin binding protein antibody
    • 47 kDa actin-binding protein antibody
    • 52 kDa phosphoprotein antibody
    • F actin binding and cytoskeleton associated protein antibody
    • Leufactin (leukocyte F-actin binding protein) antibody
    • Leufactin antibody
    • Leukocyte F actin binding protein antibody
    • Leukocyte specific protein 1 antibody
    • LSP 1 antibody
    • Lsp1 antibody
    • LSP1_HUMAN antibody
    • Lymphocyte specific antigen WP34 antibody
    • Lymphocyte specific protein 1 antibody
    • Lymphocyte specific protein pp52 antibody
    • Lymphocyte-specific antigen WP34 antibody
    • Lymphocyte-specific protein 1 antibody
    • OTTHUMP00000014138 antibody
    • OTTHUMP00000014139 antibody
    • OTTHUMP00000014140 antibody
    • OTTHUMP00000069612 antibody
    • OTTHUMP00000069614 antibody
    • OTTHUMP00000069615 antibody
    • OTTHUMP00000069616 antibody
    • pp52 antibody
    • Protein pp52 antibody
    • S37 protein antibody
    • WP 34 antibody
    • WP34 antibody
    see all

Images

  • Anti-LSP1 antibody (ab112887) at 0.05 µg/ml + Human Peripheral Lymphocytes lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 37 kDa
  • All lanes : Anti-LSP1 antibody (ab112887) at 0.05 µg/ml

    Lane 1 : Human Liver lysate
    Lane 2 : Mouse Liver lysate
    Lane 3 : Rat Liver lysate

    Lysates/proteins at 35 µg per lane.

    Developed using the ECL technique

    Predicted band size : 37 kDa

References

ab112887 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab112887.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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