Overview

  • Product name
  • Description
    Rabbit polyclonal to LSP1
  • Specificity
    This epitope affinity purified rabbit polyclonal antibody reacts predominantly with LSP1. By immunoblot analysis, a ~52 kDa immunoreactive protein from Mouse Spleen tissue lysate was detected (sample were boiled prior to subject 10% SDSpolyacrylamide gel electrophoresis). This band is abolished by the depletion of the synthetic immunizing peptide.
  • Tested applications
    Suitable for: ELISA, IP, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide:

    KLARQASIELP

    , corresponding to amino acids 246-256 of Human LSP1.

Properties

Applications

Our Abpromise guarantee covers the use of ab21637 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use a concentration of 0.1 - 1 µg/ml.
IP Use 3µg for 105 cells.
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 52 kDa.

Target

  • Function
    May play a role in mediating neutrophil activation and chemotaxis.
  • Tissue specificity
    Activated T-lymphocytes.
  • Post-translational
    modifications
    Phosphorylated by casein kinase II, protein kinase C and MAPKAPK2. Phosphorylation by PKC induces translocation from membrane to cytoplasm. Phosphorylation by MAPKAPK2 may regulate neutrophil chemotaxis.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 47 kDa actin binding protein antibody
    • 47 kDa actin-binding protein antibody
    • 52 kDa phosphoprotein antibody
    • F actin binding and cytoskeleton associated protein antibody
    • Leufactin (leukocyte F-actin binding protein) antibody
    • Leufactin antibody
    • Leukocyte F actin binding protein antibody
    • Leukocyte specific protein 1 antibody
    • LSP 1 antibody
    • Lsp1 antibody
    • LSP1_HUMAN antibody
    • Lymphocyte specific antigen WP34 antibody
    • Lymphocyte specific protein 1 antibody
    • Lymphocyte specific protein pp52 antibody
    • Lymphocyte-specific antigen WP34 antibody
    • Lymphocyte-specific protein 1 antibody
    • OTTHUMP00000014138 antibody
    • OTTHUMP00000014139 antibody
    • OTTHUMP00000014140 antibody
    • OTTHUMP00000069612 antibody
    • OTTHUMP00000069614 antibody
    • OTTHUMP00000069615 antibody
    • OTTHUMP00000069616 antibody
    • pp52 antibody
    • Protein pp52 antibody
    • S37 protein antibody
    • WP 34 antibody
    • WP34 antibody
    see all

References

This product has been referenced in:
  • Wu JL  et al. Temporal regulation of Lsp1 O-GlcNAcylation and phosphorylation during apoptosis of activated B cells. Nat Commun 7:12526 (2016). Read more (PubMed: 27555448) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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