Overview

  • Product name
  • Description
    Rabbit polyclonal to LSR
  • Host species
    Rabbit
  • Specificity
    ab191180 was affinity purified using an epitope specific to LSR immobilized on a solid support.
  • Tested applications
    Suitable for: IP, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Gorilla
  • Immunogen

    Synthetic peptide within Human LSR aa 450-500. The exact sequence is proprietary.
    Sequence:

    PALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRARRPRARSVDALDD L


    Database link: Q86X29

  • Positive control
    • WB: HeLa, 293T and Jurkat whole cell lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% Tris citrate/phosphate

    pH 7 to 8
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab191180 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-10 µg/mg of lysate.
WB 1/2000 - 1/10000. Predicted molecular weight: 71 kDa.

Target

  • Function
    Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells.
  • Sequence similarities
    Belongs to the immunoglobulin superfamily. LISCH7 family.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ILDR3 antibody
    • Immunoglobulin like domain containing receptor 3 antibody
    • Lipolysis Stimulated Lipoprotein Receptor antibody
    • Lipolysis stimulated remnant antibody
    • Lipolysis-stimulated lipoprotein receptor antibody
    • LISCH antibody
    • LISCH protein antibody
    • LISCH7 antibody
    • Liver specific bHLH Zip transcription factor antibody
    • LSR antibody
    • LSR_HUMAN antibody
    • MGC10659 antibody
    • MGC48312 antibody
    • MGC48503 antibody
    see all

Images

  • Immunoprecipitation of 293T whole cell lysate using ab191180 (lane 1) at 6µg per reaction (0.5 or 1 mg/IP; 20% of IP loaded/lane). Immunoblot analysis of LSR utilised ab191180 at 0.4 µg/ml. The lysate in lane 2 is precipitated with an IgG control antibody. Detection utilised chemiluminescence with an exposure time of 30seconds.

  • All lanes : Anti-LSR antibody (ab191180) at 0.1 µg/ml

    Lane 1 : HeLa whole cell lysate prepared using RIPA lysis buffer.
    Lane 2 : 293T whole cell lysate prepared using RIPA lysis buffer.
    Lane 3 : Jurkat whole cell lysate prepared using RIPA lysis buffer.

    Lysates/proteins at 50 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 71 kDa


    Exposure time: 3 minutes

References

ab191180 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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