Anti-LTBR antibody [3C8] - Low endotoxin, Azide free (ab171241)

Overview

  • Product name
    Anti-LTBR antibody [3C8] - Low endotoxin, Azide free
    See all LTBR primary antibodies
  • Description
    Rat monoclonal [3C8] to LTBR - Low endotoxin, Azide free
  • Tested applications
    Suitable for: Functional Studies, Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • Positive control
    • NIH/3T3 cells.
  • General notes

    Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by the LAL assay.

Properties

Applications

Our Abpromise guarantee covers the use of ab171241 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Functional Studies Use at an assay dependent concentration.

ab171241 is reported to have agonistic activity (via activation of NKκ B).

Flow Cyt Use at an assay dependent concentration.

ab171241 can be used at less than or equal to 0.5μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10e5 to 10e8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

ab18407 - Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody.

Target

  • Function
    Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.
  • Sequence similarities
    Contains 4 TNFR-Cys repeats.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD18 antibody
    • D12S370 antibody
    • LT beta R antibody
    • LTBETAR antibody
    • Ltbr antibody
    • Lymphotoxin B receptor antibody
    • Lymphotoxin beta receptor (TNFR superfamily, member 3) antibody
    • Lymphotoxin beta receptor antibody
    • Lymphotoxin-beta receptor antibody
    • TNF R III antibody
    • TNF-RIII antibody
    • TNFCR antibody
    • TNFR RP antibody
    • TNFR superfamily member 3 antibody
    • TNFR-III antibody
    • TNFR2 RP antibody
    • TNFR2RP antibody
    • TNFR3 antibody
    • TNFRII antibody
    • TNFRRP antibody
    • TNFRSF 3 antibody
    • TNFRSF3 antibody
    • TNR3_HUMAN antibody
    • Tumor necrosis factor C receptor antibody
    • Tumor necrosis factor receptor 2 related protein antibody
    • Tumor necrosis factor receptor 2-related protein antibody
    • Tumor necrosis factor receptor superfamily member 3 antibody
    • Tumor necrosis factor receptor superfamily member 3 precursor antibody
    • Tumor necrosis factor receptor type III antibody
    see all

Images

  • Flow cytometry analysis of total viable NIH/3T3 cells (10e5 to 10e8)  labeling LTBR with ab171241 (filled histogram) at 0.25µg or Rat IgG1 control (open histogram). Followed by anti-Rat IgG Biotin and Streptavidin PE.

References

ab171241 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab171241.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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