Anti-LTBR antibody [3C8] - Low endotoxin, Azide free (ab171241)
- Datasheet
- Specific References
- Protocols
Overview
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Product nameAnti-LTBR antibody [3C8] - Low endotoxin, Azide free
See all LTBR primary antibodies -
DescriptionRat monoclonal [3C8] to LTBR - Low endotoxin, Azide free
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Host speciesRat
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Tested applicationsSuitable for: Functional Studies, Flow Cytmore details
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Species reactivityReacts with: Mouse
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Immunogen
The details of the immunogen for this antibody are not available.
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Positive control
- NIH/3T3 cells.
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General notes
Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by the LAL assay.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
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Storage bufferpH: 7.20
Constituent: 100% PBS -
Concentration information loading... -
PurityProtein G purified
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ClonalityMonoclonal
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Clone number3C8
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IsotypeIgG1
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Light chain typekappa
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Research areas
Associated products
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Compatible Secondaries
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Conjugation kits
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Positive Controls
Applications
Our Abpromise guarantee covers the use of ab171241 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
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| Functional Studies | Use at an assay dependent concentration. ab171241 is reported to have agonistic activity (via activation of NKκ B). |
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| Flow Cyt | Use at an assay dependent concentration. ab171241 can be used at less than or equal to 0.5μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10e5 to 10e8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. ab18407 - Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
Target
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FunctionReceptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.
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Sequence similaritiesContains 4 TNFR-Cys repeats.
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Cellular localizationMembrane.
- Information by UniProt
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Database links
- Entrez Gene: 17000 Mouse
- SwissProt: P50284 Mouse
- Unigene: 3122 Mouse
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Alternative names
- CD18 antibody
- D12S370 antibody
- LT beta R antibody
see all
Images
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![Flow Cytometry - Anti-LTBR [3C8] antibody - Low endotoxin, Azide free (ab171241)](http://a.abcam.com/ps/products/171/ab171241/Images/ab171241-172451-ab171241.JPG)
Flow Cytometry - Anti-LTBR [3C8] antibody - Low endotoxin, Azide free (ab171241)Flow cytometry analysis of total viable NIH/3T3 cells (10e5 to 10e8) labeling LTBR with ab171241 (filled histogram) at 0.25µg or Rat IgG1 control (open histogram). Followed by anti-Rat IgG Biotin and Streptavidin PE.
Protocols
References
ab171241 has not yet been referenced specifically in any publications.
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"