Overview

  • Product name
    Anti-LTBR antibody [5G11]
    See all LTBR primary antibodies
  • Description
    Rat monoclonal [5G11] to LTBR
  • Tested applications
    Suitable for: ELISA, WB, Functional Studies, Flow Cytmore details
    Unsuitable for: IHC-Fr or IHC-P
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • General notes

    This antibody is an agonist of LTBR in vitro and is provided in a low endotoxin format.

Properties

Applications

Our Abpromise guarantee covers the use of ab65089 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.
WB 1/50. Predicted molecular weight: 45 kDa.
Functional Studies Use at an assay dependent concentration.
Flow Cyt 1/50. ab18450-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
  • Application notes
    Is unsuitable for IHC-Fr or IHC-P.
  • Target

    • Function
      Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.
    • Sequence similarities
      Contains 4 TNFR-Cys repeats.
    • Cellular localization
      Membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD18 antibody
      • D12S370 antibody
      • LT beta R antibody
      • LTBETAR antibody
      • Ltbr antibody
      • Lymphotoxin B receptor antibody
      • Lymphotoxin beta receptor (TNFR superfamily, member 3) antibody
      • Lymphotoxin beta receptor antibody
      • Lymphotoxin-beta receptor antibody
      • TNF R III antibody
      • TNF-RIII antibody
      • TNFCR antibody
      • TNFR RP antibody
      • TNFR superfamily member 3 antibody
      • TNFR-III antibody
      • TNFR2 RP antibody
      • TNFR2RP antibody
      • TNFR3 antibody
      • TNFRII antibody
      • TNFRRP antibody
      • TNFRSF 3 antibody
      • TNFRSF3 antibody
      • TNR3_HUMAN antibody
      • Tumor necrosis factor C receptor antibody
      • Tumor necrosis factor receptor 2 related protein antibody
      • Tumor necrosis factor receptor 2-related protein antibody
      • Tumor necrosis factor receptor superfamily member 3 antibody
      • Tumor necrosis factor receptor superfamily member 3 precursor antibody
      • Tumor necrosis factor receptor type III antibody
      see all

    Images

    • Detection of LT beta receptor in Wehi-167 cells. Red, black and blue line represent the isotype control, cells only and ab65089 at 10 μg/ml, respectively.

    References

    This product has been referenced in:
    • Gray CM  et al. Noncanonical NF-?B signaling is limited by classical NF-?B activity. Sci Signal 7:ra13 (2014). Read more (PubMed: 24497610) »
    • Hehlgans T  et al. Activation of the lymphotoxin-beta receptor induces NFkappaB-dependent interleukin-6 and MIP-2 secretion in mouse fibrosarcoma cells. Eur Cytokine Netw 14:103-7 (2003). Read more (PubMed: 12957791) »

    See all 2 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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