Anti-LXR alpha + LXR beta antibody (ab24532)

Overview

  • Product nameAnti-LXR alpha + LXR beta antibody
    See all LXR alpha + LXR beta primary antibodies
  • Description
    Rabbit polyclonal to LXR alpha + LXR beta
  • SpecificityThis antibody detects the alpha and beta subunits of human LXR.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide surrounding amino acid 435 of human LXR.

Properties

Applications

Our Abpromise guarantee covers the use of ab24532 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 2 - 6 µg/ml. Predicted molecular weight: 50 kDa.

Target

  • RelevanceLXR alpha and LXR beta are orphan receptors. Interaction with RXR shifts RXR from its role as a silent DNA binding partner to an active ligand binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4 type response elements characterized by direct repeats of two similar hexanuclotide half sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis. LXR alpha: Visceral organs specific expression. Strong expression was found in liver, kidney and intestine followed by spleen and to a lesser extent the adrenals. LXR beta: Ubiquitously expressed.
  • Cellular localizationNuclear
  • Database links
  • Alternative names
    • Liver X receptor alpha antibody
    • Liver X receptor beta antibody
    • LXR a antibody
    • LXR b antibody
    • LXRalpha antibody
    • LXRbeta antibody
    • NR1H2 antibody
    • NR1H3 antibody
    • Nuclear orphan receptor LXR alpha antibody
    • Nuclear orphan receptor LXR beta antibody
    • Nuclear receptor subfamily 1 group H member 2 antibody
    • Nuclear receptor subfamily 1 group H member 3 antibody
    • Oxysterols receptor LXR alpha antibody
    • Oxysterols receptor LXR beta antibody
    see all

Anti-LXR alpha + LXR beta antibody images



  • Predicted band size : 50 kDa

References for Anti-LXR alpha + LXR beta antibody (ab24532)

ab24532 has not yet been referenced specifically in any publications.

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