Overview

  • Product nameAnti-Ly49C+F+H+I antibody [14B11] (Biotin)
    See all Ly49C+F+H+I primary antibodies
  • Description
    Syrian Hamster monoclonal [14B11] to Ly49C+F+H+I (Biotin)
  • ConjugationBiotin
  • Specificityab93505 reacts with a subset of mouse Ly49 receptors and recognizes a majority of mouse NK cells. It reacts with 3 putative inhibitory members of the Ly49 family, F, I, and C and one putative activating receptor, Ly49H. It does not react with Ly49A, B, D, or G.
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • Positive control
    • Mouse splenocytes
  • General notes


    ab93505 is reported to enhance the redirected lysis of FcR+ target cells by IL-2-activated NK cells.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS, 150mM Sodium chloride, pH 7.2
  • Concentration information loading...
  • Primary antibody notesab93505 is reported to enhance the redirected lysis of FcR+ target cells by IL-2-activated NK cells.
  • ClonalityMonoclonal
  • Clone number14B11
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab93505 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 0.25µg for 105 cells.

Use 0.25µg for 105 to 108 cells in a final volume of 100µl.





ab18486-Syrian Hamster monoclonal IgG, is suitable for use as an isotype control with this antibody.

Target

  • RelevanceLy49C, Ly49F, Ly49H and Ly49I are members of the lectin like homodimeric Ly49 family of cell surface receptors. Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down regulated. These inhibitory receptors are also expressed on a subpopulation of mouse CD8+ T cells.
  • Cellular localizationPlasma membrane
  • Database links
  • Alternative names
    • 5E6 antibody
    • Cmv-1 antibody
    • Cmv1 antibody
    • Killer cell lectin like receptor 3 antibody
    • Killer cell lectin like receptor 6 antibody
    • Killer cell lectin like receptor 8 antibody
    • Killer cell lectin like receptor 9 antibody
    • Killer cell lectin-like receptor subfamily A, member 9 antibody
    • Killer cell lectin-like receptor, subfamily A, member 3 antibody
    • Killer cell lectin-like receptor, subfamily A, member 6 antibody
    • Killer cell lectin-like receptor, subfamily A, member 8 antibody
    • Klra3 antibody
    • Klra3 protein antibody
    • Klra6 antibody
    • Klra8 antibody
    • Klra9 antibody
    • Ly49 C antigen antibody
    • Ly49 F antigen antibody
    • Ly49 H antigen antibody
    • Ly49 I antigen antibody
    • Ly49c antibody
    • Ly49f antibody
    • Ly49h antibody
    • Ly49I antibody
    • LY49I1 antibody
    • Ly49u<129> antibody
    • Lymphocyte antigen 49C antibody
    • Lymphocyte antigen 49F antibody
    • Lymphocyte antigen 49H antibody
    • Lymphocyte antigen 49I antibody
    • MGC123910 antibody
    • MHC class I recognition receptor Ly49I antibody
    • Natural killer cell receptor Ly49C antibody
    • Nk-2 antibody
    • NK-2.1 antibody
    • Nk2 antibody
    • Nk2.1 antibody
    • T cell surface glycoprotein Ly 49C antibody
    • T cell surface glycoprotein Ly 49F antibody
    • T cell surface glycoprotein Ly 49H antibody
    • T cell surface glycoprotein Ly 49I antibody
    see all

References for Anti-Ly49C+F+H+I antibody [14B11] (Biotin) (ab93505)

This product has been referenced in:
  • Corral L  et al. A new monoclonal antibody reactive with several Ly49 NK cell receptors mediates redirected lysis of target cells. Hybridoma 18:359-66 (1999). Read more (PubMed: 10571266) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab93505.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"