Overview

  • Product nameAnti-LY75 antibody [MG38] (FITC)
    See all LY75 primary antibodies
  • Description
    Mouse monoclonal [MG38] to LY75 (FITC)
  • ConjugationFITC. Ex: 493nm, Em: 528nm
  • SpecificityAll leukocytes from peripheral blood show a degree of staining with ab95586 that can be minimized by using very low concentrations.
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    CR-Fn II fusion protein

  • Positive control
    • Mature dendritic cells or normal Human peripheral blood cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab95586 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 0.03µg for 105-8 cells. ab18427-Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.

Target

  • FunctionActs as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes.
  • Tissue specificityExpressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.
  • Sequence similaritiesContains 10 C-type lectin domains.
    Contains 1 fibronectin type-II domain.
    Contains 1 ricin B-type lectin domain.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C-type lectin domain family 13 member B antibody
    • CD 205 antibody
    • CD205 antibody
    • CD205 antigen antibody
    • CLEC 13B antibody
    • CLEC13B antibody
    • DEC 205 antibody
    • DEC-205 antibody
    • DEC205 antibody
    • gp200 antibody
    • gp200 MR6 antibody
    • gp200-MR6 antibody
    • LY 75 antibody
    • Ly-75 antibody
    • LY75 antibody
    • LY75_HUMAN antibody
    • Lymphocyte antigen 75 antibody
    • Renal Cell Carcinoma (gp200) antibody
    see all

Anti-LY75 antibody [MG38] (FITC) images

  • Staining of normal Human peripheral blood cells (left) or mature dendritic cells (right) with Mouse IgG2b ? Isotype Control FITC (open histogram) or 0.015 µg of ab95586 (filled histogram). Total viable cells were used for analysis.

References for Anti-LY75 antibody [MG38] (FITC) (ab95586)

ab95586 has not yet been referenced specifically in any publications.

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