Anti-LY75 antibody [SPM487], prediluted (ab28378)

Overview

  • Product name
    Anti-LY75 antibody [SPM487], prediluted
    See all LY75 primary antibodies
  • Description
    Mouse monoclonal [SPM487] to LY75, prediluted
  • Host species
    Mouse
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human LY75.
    Database link: O60449

  • Positive control
    • IHC-P: Human renal cell carcinoma and kidney tissues.
  • General notes

    For manual IHC only.

Properties

  • Form
    Prediluted
  • Storage instructions
    Shipped at 4°C. Store at +4°C. Do Not Freeze.
  • Storage buffer
    pH: 7.6
    Preservative: 0.099% Sodium azide
    Constituents: Tris buffered saline, 1% BSA
  • Concentration information loading...
  • Purification notes
    Purified from TCS by protein A/G.
  • Clonality
    Monoclonal
  • Clone number
    SPM487
  • Isotype
    IgG1
  • Light chain type
    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab28378 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/1.

Ready to use.

Boil tissue section in Citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.

Primary antibody incubation for 30 minutes at room temperature.

Target

  • Function
    Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes.
  • Tissue specificity
    Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.
  • Sequence similarities
    Contains 10 C-type lectin domains.
    Contains 1 fibronectin type-II domain.
    Contains 1 ricin B-type lectin domain.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C-type lectin domain family 13 member B antibody
    • CD 205 antibody
    • CD205 antibody
    • CD205 antigen antibody
    • CLEC 13B antibody
    • CLEC13B antibody
    • DEC 205 antibody
    • DEC-205 antibody
    • DEC205 antibody
    • gp200 antibody
    • gp200 MR6 antibody
    • gp200-MR6 antibody
    • LY 75 antibody
    • Ly-75 antibody
    • LY75 antibody
    • LY75_HUMAN antibody
    • Lymphocyte antigen 75 antibody
    • Renal Cell Carcinoma (gp200) antibody
    see all

Images

  • Formalin-fixed, paraffin-embedded human renal cell carcinoma tissue stained for LY75 using ab28378 in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human kidney tissue stained for LY75 using ab28378 at 1/100 dilution in immunohistochemical analysis.

References

ab28378 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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