Anti-Lymphocytes+Langerhans cells antibody [MS gp2] (ab27922)

Overview

  • Product name
    Anti-Lymphocytes+Langerhans cells antibody [MS gp2]
  • Description
    Mouse monoclonal [MS gp2] to Lymphocytes+Langerhans cells
  • Specificity
    ab27922 recognises an antigen on the majority of T and B lymphocytes and thymocytes, and it reacts strongly with epidermal Langerhans cells, giving a superior profile than anti MHC Class II antibodies on these cells. The antigen recognised by ab27922 is not expressed by germinal centre cells of the lymph node.
  • Tested applications
    Suitable for: IHC-Frmore details
    Unsuitable for: ELISA,Flow Cyt,IHC-P,IHC-R,Inhibition,IP,RIA or WB
  • Species reactivity
    Reacts with: Guinea pig
  • Immunogen

    Tissue/ cell preparation: Nylon wool adherent B cells (Guinea pig)

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: Tissue culture supernatant
  • Purity
    Tissue culture supernatant
  • Clonality
    Monoclonal
  • Clone number
    MS gp2
  • Myeloma
    NS1
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab27922 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr
  • Application notes

    IHC-Fr: Use at an assay dependent dilution.

    Is unsuitable for ELISA, FACS, IHC-P, IHC-R, IP, Inhib, RIA or WB. Does not functionally inhibit lymphocyte adherence to high endothelial venules in vitro.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance
      Lymphocytes have receptors for antigen and confer specificity on an immune response. Lymphocytes express receptors with varying affinity for the antigen in question. Langerhans Cells are present in the skin and process efficiently antigen but cannot present it to T cells. Langerhans cells have been shown to pick up antigen in skin and carry it via afferent lymphatic vessels to lymph nodes.

    References for Anti-Lymphocytes+Langerhans cells antibody [MS gp2] (ab27922)

    This product has been referenced in:
    • Healey DG  et al. An antigenic determinant common to lymphocytes and Langerhans cells of the guinea pig. Int Arch Allergy Appl Immunol 82:120-4 (1987). Read more (PubMed: 2433227) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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