Anti-LYPD3 antibody [SP204] Recombinant (ab183353)

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Product name

Anti-LYPD3 antibody [SP204]
See all LYPD3 primary antibodies
Description

Rabbit monoclonal [SP204] to LYPD3
Host species

Rabbit
Tested applications

Suitable for: IHC-Pmore details
Species reactivity

Reacts with: Human
Immunogen

Synthetic peptide within Human LYPD3 (C terminal). The exact sequence is proprietary.
Database link: O95274
Positive control
- Human skin, esophagus, cervix, tonsil, skin squamous cell carcinoma and cervical squamous cell carcinoma tissues
General notes

Mouse: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.

This product is a recombinant rabbit monoclonal antibody.

Form

Liquid
Storage instructions

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer

pH: 7.60
Preservative: 0.1% Sodium azide
Constituents: 98% PBS, 1% BSA
Concentration information loading...
Purification notes

Purified from TCS by protein A/G.
Clonality

Monoclonal
Clone number

SP204
Isotype

IgG
Research areas

Our Abpromise guarantee covers the use of ab183353 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application	Abreviews	Notes
IHC-P		1/100. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Function

Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression.
Tissue specificity

Expressed in placenta, skin and urothelium. Found in suprabasal keratinocytes of chronic wounds. Weak expression is found in esophagus and peripheral blood mononuclear cells. Found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression is found in the tumor component of some noninvasive superficial lesions and in invasive and metastatic urothelial cancers.
Sequence similarities

Contains 2 UPAR/Ly6 domains.
Post-translational
modifications

N-glycosylated and O-glycosylated.
Cellular localization

Cell membrane.
Target information above from: UniProt accession O95274 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
Database links
- Entrez Gene: 27076 Human
- Omim: 609484 Human
- SwissProt: O95274 Human
- Unigene: 631594 Human
Alternative names
- C4.4A antibody
- GPI-anchored metastasis-associated protein C4.4A homolog antibody
- GPI-anchored metastasis-associated protein homolog antibody
- Ly6/PLAUR domain-containing protein 3 antibody
- Lypd3 antibody
- LYPD3_HUMAN antibody
- Matrigel-induced gene C4 protein antibody
- MIG-C4 antibody
- SHINC3 antibody
see all

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LYPD3 [SP204] antibody (ab183353)

Immunohistochemical analysis of paraffin embedded Human skin tissue labeling LYPD3 with ab183353 at 1/100 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LYPD3 [SP204] antibody (ab183353)

Immunohistochemical analysis of paraffin embedded Human esophagus tissue labeling LYPD3 with ab183353 at 1/100 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LYPD3 [SP204] antibody (ab183353)

Immunohistochemical analysis of paraffin embedded Human cervix tissue labeling LYPD3 with ab183353 at 1/100 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LYPD3 [SP204] antibody (ab183353)

Immunohistochemical analysis of paraffin embedded Human tonsil tissue labeling LYPD3 with ab183353 at 1/100 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LYPD3 [SP204] antibody (ab183353)

Immunohistochemical analysis of paraffin embedded Human skin squamous cell carcinoma tissue labeling LYPD3 with ab183353 at 1/100 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LYPD3 [SP204] antibody (ab183353)

Immunohistochemical analysis of paraffin embedded Human cervical squamous cell carcinoma tissue labeling LYPD3 with ab183353 at 1/100 dilution.

ab183353 has not yet been referenced specifically in any publications.

Publishing research using ab183353? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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