Recombinant
RabMAb

Anti-LYPD3 antibody [SP208] (ab183357)

Overview

  • Product name
    Anti-LYPD3 antibody [SP208]
    See all LYPD3 primary antibodies
  • Description
    Rabbit monoclonal [SP208] to LYPD3
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Human LYPD3 (internal sequence).
    Database link: O95274

  • Positive control
    • Human skin, esophagus, tonsil, bladder, cervix, breast ductal carcinoma, skin squamous cell carcinoma and cervical squamous cell carcinoma tissues.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.60
    Preservative: 0.097% Sodium azide
    Constituents: 1% BSA, 98% PBS
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Monoclonal
  • Clone number
    SP208
  • Isotype
    IgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab183357 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression.
  • Tissue specificity
    Expressed in placenta, skin and urothelium. Found in suprabasal keratinocytes of chronic wounds. Weak expression is found in esophagus and peripheral blood mononuclear cells. Found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression is found in the tumor component of some noninvasive superficial lesions and in invasive and metastatic urothelial cancers.
  • Sequence similarities
    Contains 2 UPAR/Ly6 domains.
  • Post-translational
    modifications
    N-glycosylated and O-glycosylated.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C4.4A antibody
    • GPI-anchored metastasis-associated protein C4.4A homolog antibody
    • GPI-anchored metastasis-associated protein homolog antibody
    • Ly6/PLAUR domain-containing protein 3 antibody
    • Lypd3 antibody
    • LYPD3_HUMAN antibody
    • Matrigel-induced gene C4 protein antibody
    • MIG-C4 antibody
    • SHINC3 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human skin tissue labeling LYPD3 with ab183357 at 1/100 dilution.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human esophagus tissue labeling LYPD3 with ab183357 at 1/100 dilution.

     

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human tonsil tissue labeling LYPD3 with ab183357 at 1/100 dilution.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human bladder tissue labeling LYPD3 with ab183357 at 1/100 dilution.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human cervix tissue labeling LYPD3 with ab183357 at 1/100 dilution.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human breast ductal cell carcinoma tissue labeling LYPD3 with ab183357 at 1/100 dilution.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human skin squamous cell carcinoma tissue labeling LYPD3 with ab183357 at 1/100 dilution.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human cervical squamous cell carcinoma tissue labeling LYPD3 with ab183357 at 1/100 dilution.

     

References

ab183357 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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