Anti-APT-2 antibody (ab151578)
Key features and details
- Rabbit polyclonal to APT-2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-APT-2 antibody -
Description
Rabbit polyclonal to APT-2 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow -
Immunogen
Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- HepG2 and Raji cell lysates; 293T, A431, HeLaS3 and Molt-4 cell lines.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab151578 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 24 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 24 kDa. |
Target
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Function
May hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has lysophospholipase activity (By similarity). Deacylates GAP43. -
Sequence similarities
Belongs to the AB hydrolase superfamily. AB hydrolase 2 family. -
Cellular localization
Cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 784764 Cow
- Entrez Gene: 11313 Human
- Entrez Gene: 26394 Mouse
- Entrez Gene: 83510 Rat
- Omim: 616143 Human
- SwissProt: O95372 Human
- SwissProt: Q9WTL7 Mouse
- SwissProt: Q9QYL8 Rat
see all -
Alternative names
- Acyl protein thioesterase 2 antibody
- Acyl protein thioesterase antibody
- Acyl-protein thioesterase 2 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab151578 has been referenced in 2 publications.
- Chen S et al. Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads. Nat Commun 10:877 (2019). PubMed: 30787281
- Vujic I et al. Acyl protein thioesterase 1 and 2 (APT-1, APT-2) inhibitors palmostatin B, ML348 and ML349 have different effects on NRAS mutant melanoma cells. Oncotarget 7:7297-306 (2016). WB . PubMed: 26771141