Overview

  • Product name
    Anti-Lysozyme antibody, prediluted
    See all Lysozyme primary antibodies
  • Description
    Rabbit polyclonal to Lysozyme, prediluted
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Cat, Dog, Human, Pig, Monkey, Baboon
    Does not react with: Mouse, Rat
  • Immunogen

    Full length Human lysozyme purified from the urine of patients with monocytic leukemia.

  • Positive control
    • Tonsil, colon, or skin tissue.
  • General notes


    ab74666 labels myeloid cells, histiocytes, granulocytes, macrophages and monocytes. Ab74666 can be helpful in the identification of myeloid or monocytic acute leukaemia.

Properties

Applications

Our Abpromise guarantee covers the use of ab74666 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/1.

Ready to use. No special pretreatment is required for immunohistochemical staining of formalin-fixed tissues.

Target

  • Function
    Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
  • Involvement in disease
    Amyloidosis 8
  • Sequence similarities
    Belongs to the glycosyl hydrolase 22 family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • 1 4 beta N acetylmuramidase C antibody
    • 1 antibody
    • 4-beta-N-acetylmuramidase C antibody
    • EC 3.2.1.17 antibody
    • LYSC_HUMAN antibody
    • Lysosyme antibody
    • Lysozyme (renal amyloidosis) antibody
    • Lysozyme C antibody
    • Lysozyme C precursor antibody
    • LYZ antibody
    • LZM antibody
    • Renal amyloidosis antibody
    see all

Images

  • Formalin-fixed, paraffin-embedded human tonsil stained with ab74666 using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of myeloid cells.

References

This product has been referenced in:
  • Luan X  et al. Pseudomonas aeruginosa triggers CFTR-mediated airway surface liquid secretion in swine trachea. Proc Natl Acad Sci U S A 111:12930-5 (2014). Read more (PubMed: 25136096) »
  • Gotes J  et al. Mechanisms of systemic vasodilation by lysozyme-c in septic shock. J Appl Physiol 112:638-50 (2012). Read more (PubMed: 22096116) »

See all 2 Publications for this product

Customer reviews and Q&As

Thank you for contacting us. The IHC-P protocol for ab74666 is as follows:

1. Deparaffinize and rehydrate tissue section.
2. Wash 2 times in buffer.
3. If required, incubate tissue in digestive enzyme (or appropriate pretreatment). ...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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