Anti-LYVE1 antibody (Biotin) (ab37288)

Overview

  • Product nameAnti-LYVE1 antibody (Biotin)
    See all LYVE1 primary antibodies
  • Description
    Rabbit polyclonal to LYVE1 (Biotin)
  • ConjugationBiotin
  • Tested applicationsSuitable for: Flow Cyt, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Recombinant fragment (His-tag) corresponding to Mouse LYVE1.
    Sequence:

    ADLVQDLSISTCRIMGVALVGRNKNPQMNFTEANEACKMLGLTLASRDQV ESAQKSGFETCSYGWVGEQFSVIPRIFSNPRCGKNGKGVLIWNAPSSQKF KAYCHNSSDTWVNSCIPEIVTTFYPVLDTQTPATEFSVSSSAYLASSPDS TTPVSATTRAPPLTSMARKTKKICITEVYTEPITMATETEAFVASGAAFK NEAAGHHHHHH


    Database link: Q8BHC0

Properties

  • FormLyophilised:The biotinylated antibody should be reconstituted to a concentration of 50 µg/ml with sterile PBS solution containing 0.1% BSA. This solution can be stored at 4°C for at least one month without detectable loss of activity. Frozen aliquots of this solution are stable for at least 6 months when kept at -20°C.
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferpH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 0.1% BSA, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab37288 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use a concentration of 3 - 10 µg/ml. ab200208-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
ICC/IF 1/50.

Target

  • FunctionLigand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.
  • Tissue specificityMainly expressed in endothelial cells lining lymphatic vessels.
  • Sequence similaritiesContains 1 Link domain.
  • Post-translational
    modifications
    O-glycosylated.
  • Cellular localizationMembrane. Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand-dependent internalization and recycling at the cell surface.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cell surface retention sequence-binding protein 1 antibody
    • CRSBP 1 antibody
    • CRSBP-1 antibody
    • CRSBP1 antibody
    • extracellular link domain containing 1 antibody
    • extracellular link domain-containing 1 antibody
    • Extracellular link domain-containing protein 1 antibody
    • HAR antibody
    • Hyaluronic acid receptor antibody
    • Lymphatic endothelium specific hyaluronan receptor antibody
    • lymphatic vessel endothelial hyaluronan receptor 1 antibody
    • Lymphatic vessel endothelial hyaluronic acid receptor 1 antibody
    • LYVE 1 antibody
    • LYVE-1 antibody
    • LYVE1 antibody
    • LYVE1_HUMAN antibody
    • XLKD1 antibody
    see all

References for Anti-LYVE1 antibody (Biotin) (ab37288)

ab37288 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: RT°C
Sample Mouse Cell (Kidney)
Specification Kidney
Permeabilization Yes - triton x-100
Fixative Paraformaldehyde
Username

Mrs. Amy Vergis

Verified customer

Submitted Feb 29 2008

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"