Anti-LZTS1 antibody - N-terminal (ab171452)

Overview

  • Product name
    Anti-LZTS1 antibody - N-terminal
    See all LZTS1 primary antibodies
  • Description
    Rabbit polyclonal to LZTS1 - N-terminal
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human LZTS1 aa 76-105 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q9Y250

  • Positive control
    • Human placenta tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab171452 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 67 kDa.

Target

  • Function
    Involved in the regulation of cell growth. May stabilize the active CDC2-cyclin B1 complex and thereby contribute to the regulation of the cell cycle and the prevention of uncontrolled cell proliferation. May act as a tumor suppressor.
  • Tissue specificity
    Highly expressed in testis, prostate, spleen, thymus, ovary and brain. Detected at lower levels in heart, placenta, small intestine, colon, liver, kidney, skeletal muscle and pancreas. Not detectable in primary tumors from breast and prostate and in many cancer cell lines.
  • Sequence similarities
    Belongs to the LZTS family.
  • Post-translational
    modifications
    Phorphorylated on serine residues. Hyperphosphorylated by the cAMP-dependent kinase PKA during cell-cycle progression.
  • Cellular localization
    Cytoplasm. Cell membrane. Cell projection > dendritic spine. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse. Associated with the plasma membrane and with microtubules. Detected in dendritic spines, especially in the postsynaptic density.
  • Information by UniProt
  • Database links
  • Alternative names
    • F37 antibody
    • F37/esophageal cancer related gene coding leucine zipper motif antibody
    • F37/esophageal cancer-related gene-coding leucine-zipper motif antibody
    • Fez1 antibody
    • Leucine zipper putative tumor suppressor 1 antibody
    • Lzts1 antibody
    • LZTS1_HUMAN antibody
    • Psdzip70 antibody
    see all

Images

  • Anti-LZTS1 antibody - N-terminal (ab171452) at 1/100 dilution + Human placenta tissue lysate at 35 µg

    Predicted band size : 67 kDa

References

ab171452 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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