Overview

  • Product name
    Anti-LZTS2 antibody
  • Description
    Rabbit polyclonal to LZTS2
  • Specificity
    This antibody is predicted to not cross-react with other LZTS family members.
  • Tested applications
    Suitable for: WB, ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to 19 amino acids near the N-terminus of Human LZTS2 (NP_115805).

  • Positive control
    • Human kidney tissue lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG

Applications

Our Abpromise guarantee covers the use of ab124191 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 73 kDa.
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use at an assay dependent concentration.

Target

  • Function
    Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
  • Tissue specificity
    Highly expressed in prostate and testis, and at slightly lower levels in spleen, thymus, uterus, small intestine and colon.
  • Sequence similarities
    Belongs to the LZTS2 family.
  • Cellular localization
    Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Localized to the centrosome throughout the cell cycle. Localized to the midbody in cells undergoing cytokinesis.
  • Information by UniProt
  • Database links
  • Alternative names
    • hLZTS2 antibody
    • KIAA1813 antibody
    • LAPSER1 antibody
    • Leucine zipper putative tumor suppressor 2 antibody
    • LZTS2 antibody
    • LZTS2_HUMAN antibody
    • OTTHUMP00000020289 antibody
    • Protein LAPSER1 antibody
    • RP11-108L7.8 antibody
    see all

Anti-LZTS2 antibody images

  • Immunofluorescence of LZTS2 in Human kidney tissue with ab124191 at 20 ug/mL.
  • Immunohistochemistry of LZTS2 in Human kidney tissue with ab124191 at 2.5 μg/mL.

  • Anti-LZTS2 antibody (ab124191) at 1 µg/ml + Human kidney tissue lysate at 15 µg

    Predicted band size : 73 kDa

References for Anti-LZTS2 antibody (ab124191)

ab124191 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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