Overview

  • Product nameAnti-LZTS2 antibody
    See all LZTS2 primary antibodies
  • Description
    Rabbit polyclonal to LZTS2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Goat, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 72-121 (PLCPAVPPRK AVPVTSFTYI NEDFRTESPP SPSSDVEDAR EQRAHNAHLR) of Human LZTS2 (NP_115805)

  • Positive control
    • Human fetal spleen lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG

Applications

Our Abpromise guarantee covers the use of ab94864 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 73 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionNegative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
  • Tissue specificityHighly expressed in prostate and testis, and at slightly lower levels in spleen, thymus, uterus, small intestine and colon.
  • Sequence similaritiesBelongs to the LZTS2 family.
  • Cellular localizationCytoplasm. Cytoplasm > cytoskeleton > centrosome. Localized to the centrosome throughout the cell cycle. Localized to the midbody in cells undergoing cytokinesis.
  • Information by UniProt
  • Database links
  • Alternative names
    • hLZTS2 antibody
    • KIAA1813 antibody
    • LAPSER1 antibody
    • Leucine zipper putative tumor suppressor 2 antibody
    • LZTS2 antibody
    • LZTS2_HUMAN antibody
    • OTTHUMP00000020289 antibody
    • Protein LAPSER1 antibody
    • RP11-108L7.8 antibody
    see all

Anti-LZTS2 antibody images

  • Anti-LZTS2 antibody (ab94864) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal spleen lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 73 kDa

References for Anti-LZTS2 antibody (ab94864)

ab94864 has not yet been referenced specifically in any publications.

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