Anti-M6PR (cation independent) antibody [2G11] (ab2733)

ab2733 has been referenced in 45 publications.

• Allison R  et al. Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia. J Cell Biol 216:1337-1355 (2017). IF ; Human . PubMed: 28389476
• Fuse A  et al. VPS29-VPS35 intermediate of retromer is stable and may be involved in the retromer complex assembly process. FEBS Lett 589:1430-6 (2015). PubMed: 25937119
• Munson MJ  et al. mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival. EMBO J 34:2272-90 (2015). PubMed: 26139536
• Garvalov BK  et al. PHD3 regulates EGFR internalization and signalling in tumours. Nat Commun 5:5577 (2014). PubMed: 25420589
• Tsika E  et al. Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration. Hum Mol Genet N/A:N/A (2014). PubMed: 24740878
• Alsalem JA  et al. Characterization of vitamin D production by human ocular barrier cells. Invest Ophthalmol Vis Sci 55:2140-7 (2014). Human . PubMed: 24576880
• Huang CY  et al. ANG II promotes IGF-IIR expression and cardiomyocyte apoptosis by inhibiting HSF1 via JNK activation and SIRT1 degradation. Cell Death Differ 21:1262-74 (2014). PubMed: 24786827
• Wang Y  et al. [Ca2+]i elevation and oxidative stress induce KCNQ1 protein translocation from the cytosol to the cell surface and increase slow delayed rectifier (IKs) in cardiac myocytes. J Biol Chem 288:35358-71 (2013). PubMed: 24142691
• Hirst J  et al. Interaction between AP-5 and the hereditary spastic paraplegia proteins SPG11 and SPG15. Mol Biol Cell 24:2558-69 (2013). PubMed: 23825025
• Baginska J  et al. Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia. Proc Natl Acad Sci U S A 110:17450-5 (2013). WB ; Human . PubMed: 24101526
• Andersen MN  et al. A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein. J Biol Chem 288:36841-54 (2013). PubMed: 24214981
• Leisi R  et al. Parvovirus B19 uptake is a highly selective process controlled by VP1u, a novel determinant of viral tropism. J Virol 87:13161-7 (2013). Human . PubMed: 24067971
• Khundadze M  et al. A hereditary spastic paraplegia mouse model supports a role of ZFYVE26/SPASTIZIN for the endolysosomal system. PLoS Genet 9:e1003988 (2013). Mouse . PubMed: 24367272
• Guo Q  et al. Amyloid Precursor Protein Revisited: NEURON-SPECIFIC EXPRESSION AND HIGHLY STABLE NATURE OF SOLUBLE DERIVATIVES. J Biol Chem 287:2437-45 (2012). PubMed: 22144675
• Scharadin TM  et al. TIG3 Tumor Suppressor-Dependent Organelle Redistribution and Apoptosis in Skin Cancer Cells. PLoS One 6:e23230 (2011). ICC/IF ; Human . PubMed: 21858038
• Progida C  et al. Rab7b controls trafficking from endosomes to the TGN. J Cell Sci 123:1480-91 (2010). ICC/IF ; Human . PubMed: 20375062
• Lee JH  et al. Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations. Cell : (2010). ICC/IF ; Mouse . PubMed: 20541250
• Casari C  et al. The dominant-negative von Willebrand factor gene deletion p.P1127_C1948delinsR: molecular mechanism and modulation. Blood 116:5371-6 (2010). ICC/IF ; African green monkey . PubMed: 20570857
• Wassmer T  et al. The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network. Dev Cell 17:110-22 (2009). ICC/IF ; Human . PubMed: 19619496
• Mardakheh FK  et al. Spred2 interaction with the late endosomal protein NBR1 down-regulates fibroblast growth factor receptor signaling. J Cell Biol 187:265-77 (2009). ICC/IF ; Human . PubMed: 19822672
• Feldman R & Martinez JD Growth suppression by ursodeoxycholic acid involves caveolin-1 enhanced degradation of EGFR. Biochim Biophys Acta 1793:1387-94 (2009). PubMed: 19446582
• Mairhofer M  et al. Stomatin-like protein-1 interacts with stomatin and is targeted to late endosomes. J Biol Chem 284:29218-29 (2009). ICC/IF ; Human . PubMed: 19696025
• Dubé M  et al. Suppression of Tetherin-restricting activity upon human immunodeficiency virus type 1 particle release correlates with localization of Vpu in the trans-Golgi network. J Virol 83:4574-90 (2009). ICC/IF ; Human . PubMed: 19244337
• Gomez TS & Billadeau DD A FAM21-containing WASH complex regulates retromer-dependent sorting. Dev Cell 17:699-711 (2009). ICC/IF ; Human . PubMed: 19922874
• Poirier S  et al. Dissection of the endogenous cellular pathways of PCSK9-induced low density lipoprotein receptor degradation: evidence for an intracellular route. J Biol Chem 284:28856-64 (2009). PubMed: 19635789
• Pfender NA  et al. Route of Uptake of Palmitoylated Encephalitogenic Peptides of Myelin Proteolipid Protein by Antigen-Presenting Cells: Importance of the Type of Bond between Lipid Chain and Peptide and Relevance to Autoimmunity. J Immunol 180:1398-404 (2008). ICC/IF ; Mouse . PubMed: 18209034
• Gu F  et al. From the Cover: Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers. Proc Natl Acad Sci U S A 105:2586-91 (2008). ICC/IF ; Human . PubMed: 18272481
• Poirier S  et al. The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2. J Biol Chem 283:2363-72 (2008). ICC/IF ; Human . PubMed: 18039658
• Fenton RA  et al. Acute regulation of aquaporin-2 phosphorylation at Ser-264 by vasopressin. Proc Natl Acad Sci U S A 105:3134-3139 (2008). IHC-FoFr ; Rat . PubMed: 18287043
• Ramirez DM  et al. Neuronal expression and subcellular localization of cholesterol 24-hydroxylase in the mouse brain. J Comp Neurol 507:1676-93 (2008). ICC/IF . PubMed: 18241055
• Bereczky Z  et al. Factor XDebrecen: Gly204Arg mutation in factor X causes the synthesis of a non-secretable protein and severe factor X deficiency. Haematologica 93:299-302 (2008). ICC/IF ; Human . PubMed: 18245654
• Styers ML  et al. Depletion of beta-COP reveals a role for COP-I in compartmentalization of secretory compartments and in biosynthetic transport of caveolin-1. Am J Physiol Cell Physiol 294:C1485-98 (2008). PubMed: 18385291
• Pérez-Victoria FJ  et al. Requirement of the Human GARP Complex for Mannose 6-phosphate-receptor-dependent Sorting of Cathepsin D to Lysosomes. Mol Biol Cell 19:2350-62 (2008). ICC/IF ; Human . PubMed: 18367545
• Clarke JH  et al. Localization of Phosphatidylinositol phosphate Kinase II{gamma} in kidney to a membrane trafficking compartment within specialized cells of the nephron. Am J Physiol Renal Physiol : (2008). PubMed: 18753295
• Da Silva CA  et al. TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation. J Immunol 181:4279-86 (2008). ICC/IF ; Human . PubMed: 18768886
• Derby MC  et al. The trans-Golgi network golgin, GCC185, is required for endosome-to-Golgi transport and maintenance of Golgi structure. Traffic 8:758-73 (2007). PubMed: 17488291
• Nassoury N  et al. The cellular trafficking of the secretory proprotein convertase PCSK9 and its dependence on the LDLR. Traffic 8:718-32 (2007). ICC/IF . PubMed: 17461796
• Lieu ZZ  et al. The golgin GCC88 is required for efficient retrograde transport of cargo from the early endosomes to the trans-Golgi network. Mol Biol Cell 18:4979-91 (2007). ICC/IF ; Human . PubMed: 17914056
• Young AR  et al. Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes. J Cell Sci 119:3888-900 (2006). PubMed: 16940348
• Benjannet S  et al. The proprotein convertase (PC) PCSK9 is inactivated by furin and/or PC5/6A: functional consequences of natural mutations and post-translational modifications. J Biol Chem 281:30561-72 (2006). PubMed: 16912035
• Ghosh M  et al. Identification of the expressed form of human cytosolic phospholipase A2beta (cPLA2beta): cPLA2beta3 is a novel variant localized to mitochondria and early endosomes. J Biol Chem 281:16615-24 (2006). PubMed: 16617059
• Hombach-Klonisch S  et al. Relaxin enhances the oncogenic potential of human thyroid carcinoma cells. Am J Pathol 169:617-32 (2006). PubMed: 16877360
• Dugast M  et al. AP2 clathrin adaptor complex, but not AP1, controls the access of the major histocompatibility complex (MHC) class II to endosomes. J Biol Chem 280:19656-64 (2005). PubMed: 15749704
• Liu Q  et al. Receptor signaling and endocytosis are differentially regulated by somatostatin analogs. Mol Pharmacol 68:90-101 (2005). PubMed: 15855408
• Arighi CN  et al. Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor. J Cell Biol 165:123-33 (2004). PubMed: 15078903