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- mSin3A antibody (ab3479)
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Product Name
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mSin3A antibody
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See all mSin3A antibodies (5)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to mSin3A
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Immunogen
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Synthetic peptide: MKRRLDDQESDVYAAQQRR, corresponding to amino acids 1-19 of Mouse mSin3A.
BLAST 'MKRRLDDQESDVYAAQQRR' with  or 
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Reacts with
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Hu, Ms
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Tested applications
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IP, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IP: Use at an assay dependent dilution.
WB: Use at a concentration of 0.5 µg/ml. Detects a band of approximately 150 kDa (predicted molecular weight: 145 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Nuclear. Nucleolus. Note=Recruited to the nucleolus by SAP30L.
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Research areas
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Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Chromatin and Nuclear Signaling >> Transcription >> Co-factors
Chromatin and Nuclear Signaling >> Transcription >> Other factors
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Relevance
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Mammalian Sin 3 (mSin 3) is a protein closely related to the yeast SIN3 repressor protein involved in the transcriptional repression of many genes. There are two mammalian isoforms, mSin 3A and mSin 3B. Containing 4 paired amphipathic helix domains (PAH domains), mSin 3A and mSin 3B have been shown to directly interact with several other transcriptional repressor proteins including HDAC 1, HDAC 2, RbAp 46, the methyl CpG binding protein MeCP 2, the Mad/Max heterodimer, and the corepressors silencing mediator of retinoic acid & thyroid hormone receptor (SMRT) and nuclear receptor corepressor (N-CoR).
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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PBS, 1 mg/ml BSA, 0.05% sodium azide Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this mSin3A antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for mSin3A antibody images, references, products related to ab3479 and other tools.
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mSin3A antibody images:
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 - mSin3A antibody (ab3479)
Western blot of mSin3A on K562 cell extract using ab3479.
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Search PubMed (MEDLINE) for references to mSin3A
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mSin3A antibody - more information
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Customer reviews (feedback) regarding mSin3A antibody |
Customer FAQs regarding mSin3A antibody |
Protocols for mSin3A antibody |
Price and availability of products related to mSin3A antibody |
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mSin3A antibody - related products:
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mSin3A antibody - other tools:
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Contact Abcam with a Technical Enquiry about mSin3A antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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