Overview

  • Product name
  • Description
    Rabbit polyclonal to MACC1
  • Tested applications
    Suitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A synthetic peptide corresponding to an internal region of Human MACC1 protein.

  • Positive control
    • Human liver tissue, Mouse liver lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab106005 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 97 kDa.
ELISA 1/10000 - 1/40000.
IHC-P Use a concentration of 2.5 µg/ml.

Target

  • Function
    Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cell motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo.
  • Tissue specificity
    Preferentially expressed in metastasizing tumors.
  • Sequence similarities
    Contains 1 SH3 domain.
  • Cellular localization
    Cytoplasm. Nucleus. Mainly found in the cytoplasm in non-metastasizing tumors.
  • Information by UniProt
  • Database links
  • Alternative names
    • 7A5 antibody
    • MACC1 antibody
    • MACC1_HUMAN antibody
    • Metastasis associated in colon cancer 1 antibody
    • Metastasis-associated in colon cancer protein 1 antibody
    • OTTHUMP00000201891 antibody
    • Putative binding protein 7a5 antibody
    • SH3 domain-containing protein 7a5 antibody
    • SH3BP4L antibody
    see all

Images

  • Lane 1 : Anti-MACC1 antibody (ab106005) at 1 µg/ml
    Lane 2 : Anti-MACC1 antibody (ab106005) at 2 µg/ml

    Lane 1 : Mouse liver tissue lysate
    Lane 2 : Mouse liver tissue lysate


    Predicted band size : 97 kDa
  • Immunohistochemical analysis of paraffin embedded Human liver tissue labelled with ab106005 at 2.5µg/ml.

References

ab106005 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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