Anti-Macro H2A.2 antibody (ab102126)


  • Product nameAnti-Macro H2A.2 antibody
    See all Macro H2A.2 primary antibodies
  • Description
    Rabbit polyclonal to Macro H2A.2
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Cow
  • Immunogen

    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 197-340 of Human Macro H2A.2 (AAH16172).

  • Positive control
    • A431 whole cell lysate, TOV-21G xenograft


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
    Constituents: 20% Glycerol, 1% BSA, PBS, pH 7
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products


Our Abpromise guarantee covers the use of ab102126 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 40 kDa.
IHC-P 1/100 - 1/500. Suggested antigen retrieval using heat mediated 10mM Citrate buffer or Tris-EDTA buffer (pH 8.0)


  • FunctionVariant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
  • Sequence similaritiesContains 1 histone H2A domain.
    Contains 1 Macro domain.
  • Cellular localizationNucleus. Chromosome. Enriched in inactive X chromosome chromatin and in senescence-associated heterochromatin.
  • Information by UniProt
  • Database links
  • Alternative names
    • Core histone macro H2A2.2 antibody
    • Core histone macro-H2A.2 antibody
    • Core histone macroH2A2.2 antibody
    • H2A histone family member Y2 antibody
    • H2AFY2 antibody
    • H2AW_HUMAN antibody
    • Histone macroH2A2 antibody
    • Macro H2A2 antibody
    • MacroH2A.2 antibody
    • MacroH2A2 antibody
    • mH2A2 antibody
    see all

Anti-Macro H2A.2 antibody images

  • Anti-Macro H2A.2 antibody (ab102126) at 1/1000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 40 kDa
  • Immunohistochemical analysis of paraffin-embedded TOV-21G xenograft, using ab102126 at 1/100 dilution.

References for Anti-Macro H2A.2 antibody (ab102126)

ab102126 has not yet been referenced specifically in any publications.

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Please accept my apologies for the long delay of my reply. I have been in contact with the source of this antibody regarding the additional band between 72 and 55 kDa. We suspect that this band may be du...

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Application ChIP
Sample Mouse Cell lysate - whole cell (ES)
Specification ES
Type Cross-linking (X-ChIP)
Duration of cross-linking step: 10 minute(s) and 0 second(s)
Specification of the cross-linking agent: Formaldehyde
Detection step Real-time PCR
Positive control No
Negative control macroH2a2-/- ES cells
IgG ab

Abcam user community

Verified customer

Submitted Nov 09 2011

I am very pleased to hear you would like to accept our offer and test ab4173 & ab102126 in mouse samples. This code will be worth the price you pay for ab4173 & ab102126 and can be used with any single future primary antibody purchase before the expira...

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