Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 antibody (ab9927)

Overview

  • Product nameAnti-Macrophage Inflammatory Protein 1 alpha / CCL3 antibody
    See all Macrophage Inflammatory Protein 1 alpha / CCL3 primary antibodies
  • Description
    Rabbit polyclonal to Macrophage Inflammatory Protein 1 alpha / CCL3
  • Tested applicationsSuitable for: ELISA, Neutralising, WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Highly pure (>98%) recombinant mMIP-1a (Mousemacrophage inflammatory protein-1 alpha)

Properties

Applications

Our Abpromise guarantee covers the use of ab9927 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use a concentration of 0.5 µg/ml. (using 100µl/well antibody solution). Allows the detection of 0.2 - 0.4 ng/well of recombinant mMIP-1a.
Neutralising Use a concentration of 2 - 5 µg/ml. for one-half maximal inhibition [ND50] of the biological activity of mMIP-1a (10 ng/ml).
WB Use a concentration of 0.1 - 0.2 µg/ml.

Target

  • FunctionMonokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
  • Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.
  • Post-translational
    modifications
    N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • C C motif chemokine 3 antibody
    • CCL 3 antibody
    • CCL3 antibody
    • CCL3_HUMAN antibody
    • Chemokine C C motif ligand 3 antibody
    • G0/G1 switch regulatory protein 19 1 antibody
    • G0/G1 switch regulatory protein 19-1 antibody
    • G0S19 1 antibody
    • G0S19 1 protein antibody
    • Heparin binding chemotaxis protein antibody
    • L2G25B antibody
    • LD78 alpha antibody
    • LD78-alpha(4-69) antibody
    • LD78alpha antibody
    • Macrophage inflammatory protein 1 alpha antibody
    • Macrophage inflammatory protein 1-alpha antibody
    • MIP 1 alpha antibody
    • MIP 1A antibody
    • MIP-1-alpha antibody
    • MIP-1-alpha(4-69) antibody
    • MIP1A antibody
    • PAT 464.1 antibody
    • SCYA 3 antibody
    • SCYA3 antibody
    • SIS alpha antibody
    • SIS beta antibody
    • SIS-beta antibody
    • Small inducible cytokine A3 antibody
    • small inducible cytokine A3 (homologous to mouse Mip-1a) antibody
    • Small-inducible cytokine A3 antibody
    • Tonsillar lymphocyte LD78 alpha protein antibody
    see all

References for Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 antibody (ab9927)

ab9927 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your reply.

For both antibodies, we guarantee them on mouse samples, but we have not necessarily tested them in in-vivo studies.

For ab9927, we recommend to start with a concentration of 2 - 5 µg/ml. for one-half m...

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Thank you for contacting Abcam.

All of the antibodies that you mentioned are guaranteed under our Abpromise to work in a Neutralizing assay, in various species:

ab89546 - Works human samples
ab9673 – Works in human samples Read More

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I am very pleased to hear you would like to accept our offer and test ab25128 in IF. This code will give you: 1 free PRIMARY ANTIBODY before the expiration date. To redeem this offer, please ...

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The band should be at approx 7.8 kDa. As far as a control you could use recombinant mMurine MIP1-alpha or the following tissues that should express Murine MIP1 alpha : Activated T-Cells, B-Cells, Langerhans cells, neutrophils, and macrophages all pro...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"