Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 antibody (ab9927)

Overview

  • Product name
    Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 antibody
    See all Macrophage Inflammatory Protein 1 alpha / CCL3 primary antibodies
  • Description
    Rabbit polyclonal to Macrophage Inflammatory Protein 1 alpha / CCL3
  • Tested applications
    Suitable for: ELISA, Neutralising, WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Highly pure (>98%) recombinant mMIP-1a (Mousemacrophage inflammatory protein-1 alpha)

Properties

Applications

Our Abpromise guarantee covers the use of ab9927 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use a concentration of 0.5 µg/ml. (using 100µl/well antibody solution). Allows the detection of 0.2 - 0.4 ng/well of recombinant mMIP-1a.
Neutralising Use a concentration of 2 - 5 µg/ml. for one-half maximal inhibition [ND50] of the biological activity of mMIP-1a (10 ng/ml).
WB Use a concentration of 0.1 - 0.2 µg/ml.

Target

  • Function
    Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
  • Sequence similarities
    Belongs to the intercrine beta (chemokine CC) family.
  • Post-translational
    modifications
    N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • C C motif chemokine 3 antibody
    • CCL 3 antibody
    • CCL3 antibody
    • CCL3_HUMAN antibody
    • Chemokine C C motif ligand 3 antibody
    • G0/G1 switch regulatory protein 19 1 antibody
    • G0/G1 switch regulatory protein 19-1 antibody
    • G0S19 1 antibody
    • G0S19 1 protein antibody
    • Heparin binding chemotaxis protein antibody
    • L2G25B antibody
    • LD78 alpha antibody
    • LD78-alpha(4-69) antibody
    • LD78alpha antibody
    • Macrophage inflammatory protein 1 alpha antibody
    • Macrophage inflammatory protein 1-alpha antibody
    • MIP 1 alpha antibody
    • MIP 1A antibody
    • MIP-1-alpha antibody
    • MIP-1-alpha(4-69) antibody
    • MIP1A antibody
    • PAT 464.1 antibody
    • SCYA 3 antibody
    • SCYA3 antibody
    • SIS alpha antibody
    • SIS beta antibody
    • SIS-beta antibody
    • Small inducible cytokine A3 antibody
    • small inducible cytokine A3 (homologous to mouse Mip-1a) antibody
    • Small-inducible cytokine A3 antibody
    • Tonsillar lymphocyte LD78 alpha protein antibody
    see all

References

ab9927 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Thank you for your reply.

For both antibodies, we guarantee them on mouse samples, but we have not necessarily tested them in in-vivo studies.

For ab9927, we recommend to start with a concentration of 2 - 5 µg/ml. for one-half m...

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Thank you for contacting Abcam.

All of the antibodies that you mentioned are guaranteed under our Abpromise to work in a Neutralizing assay, in various species:

ab89546 - Works human samples
ab9673 – Works in human samples Read More

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I am very pleased to hear you would like to accept our offer and test ab25128 in IF. This code will give you: 1 free PRIMARY ANTIBODY before the expiration date. To redeem this offer, please ...

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The band should be at approx 7.8 kDa. As far as a control you could use recombinant mMurine MIP1-alpha or the following tissues that should express Murine MIP1 alpha : Activated T-Cells, B-Cells, Langerhans cells, neutrophils, and macrophages all pro...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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