Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 antibody (Biotin) (ab84441)

Overview

  • Product name
    Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 antibody (Biotin)
    See all Macrophage Inflammatory Protein 1 alpha / CCL3 primary antibodies
  • Description
    Goat polyclonal to Macrophage Inflammatory Protein 1 alpha / CCL3 (Biotin)
  • Conjugation
    Biotin
  • Tested applications
    Suitable for: ELISA, Sandwich ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Highly pure (>98%) recombinant full length Human protein

Properties

Applications

Our Abpromise guarantee covers the use of ab84441 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
Sandwich ELISA
WB
  • Application notes
    ELISA: Use at a concentration of 0.25 - 1 µg/ml. Detection limit for recombinant Human protein: 0.2 - 0.4 ng/well, using 100 µl/well antibody solution.
    sELISA: Use at a concentration of 0.25 - 1 µg/ml. Detection limit for recombinant Human protein: 0.2 - 0.4 ng/well, using 100 µl/well antibody solution.
    WB: Use at a concentration of 0.1 - 0.2 µg/ml. Detection limit for recombinant Human protein: 1.5 - 3.0 ng/lane, under reducing or non-reducing conditions. Predicted molecular weight: 11 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
    • Sequence similarities
      Belongs to the intercrine beta (chemokine CC) family.
    • Post-translational
      modifications
      N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • C C motif chemokine 3 antibody
      • CCL 3 antibody
      • CCL3 antibody
      • CCL3_HUMAN antibody
      • Chemokine C C motif ligand 3 antibody
      • G0/G1 switch regulatory protein 19 1 antibody
      • G0/G1 switch regulatory protein 19-1 antibody
      • G0S19 1 antibody
      • G0S19 1 protein antibody
      • Heparin binding chemotaxis protein antibody
      • L2G25B antibody
      • LD78 alpha antibody
      • LD78-alpha(4-69) antibody
      • LD78alpha antibody
      • Macrophage inflammatory protein 1 alpha antibody
      • Macrophage inflammatory protein 1-alpha antibody
      • MIP 1 alpha antibody
      • MIP 1A antibody
      • MIP-1-alpha antibody
      • MIP-1-alpha(4-69) antibody
      • MIP1A antibody
      • PAT 464.1 antibody
      • SCYA 3 antibody
      • SCYA3 antibody
      • SIS alpha antibody
      • SIS beta antibody
      • SIS-beta antibody
      • Small inducible cytokine A3 antibody
      • small inducible cytokine A3 (homologous to mouse Mip-1a) antibody
      • Small-inducible cytokine A3 antibody
      • Tonsillar lymphocyte LD78 alpha protein antibody
      see all

    References

    ab84441 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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