Anti-Macrophage Inflammatory Protein 1 beta antibody (Biotin) (ab84439)

Overview

  • Product name
    Anti-Macrophage Inflammatory Protein 1 beta antibody (Biotin)
    See all Macrophage Inflammatory Protein 1 beta primary antibodies
  • Description
    Goat polyclonal to Macrophage Inflammatory Protein 1 beta (Biotin)
  • Conjugation
    Biotin
  • Tested applications
    Suitable for: WB, ELISA, Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Highly pure (>98%) recombinant full length Human protein

Properties

Applications

Our Abpromise guarantee covers the use of ab84439 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
Sandwich ELISA
  • Application notes
    ELISA: Use at a concentration of 0.25 - 1 µg/ml. Detection limit for recombinant Human protein: 0.2 - 0.4 ng/well, using 100 µl/well antibody solution.
    sELISA: Use at a concentration of 0.25 - 1 µg/ml. Detection limit for recombinant Human protein: 0.2 - 0.4 ng/well, using 100 µl/well antibody solution.
    WB: Use at a concentration of 0.1 - 0.2 µg/ml. Detection limit for recombinant Human protein: 1.5 - 3.0 ng/lane, under reducing or non-reducing conditions. Predicted molecular weight: 10 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
    • Sequence similarities
      Belongs to the intercrine beta (chemokine CC) family.
    • Post-translational
      modifications
      N-terminal processed form MIP-1-beta(3-69) is produced by proteolytic cleavage after secretion from peripheral blood lymphocytes.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • MIP 1 beta antibody
      • Secreted protein G 26 antibody
      • ACT 2 antibody
      • ACT-2 antibody
      • ACT2 antibody
      • AT744.1 antibody
      • AT744.2 antibody
      • C C motif chemokine 4 antibody
      • C C motif chemokine 4 like antibody
      • C C motif chemokine ligand 4 like 1 antibody
      • C C motif chemokine ligand 4 like 2 antibody
      • CC chemokine ligand 4 antibody
      • CC chemokine ligand 4L1 antibody
      • CC chemokine ligand 4L1d2 antibody
      • CC chemokine ligand 4L2 antibody
      • CCL4 antibody
      • CCL4_HUMAN antibody
      • ccl4l 1 antibody
      • CCL4L antibody
      • CCL4L1 antibody
      • Chemokine (C C motif) ligand 4 antibody
      • Chemokine (C C motif) ligand 4 like 1 antibody
      • Chemokine (C C motif) ligand 4 like 1, telomeric antibody
      • Chemokine (C C motif) ligand 4 like 2 antibody
      • Chemokine CC Motif Ligand 4 antibody
      • G 26 antibody
      • G 26 T lymphocyte secreted protein antibody
      • G-26 T-lymphocyte-secreted protein antibody
      • HC21 antibody
      • Immune activation 2 antibody
      • LAG 1 antibody
      • LAG-1 antibody
      • LAG1 antibody
      • Lymphocyte activation gene 1 antibody
      • Lymphocyte activation gene 1 protein antibody
      • Macrophage inflammatory protein 1 beta antibody
      • Macrophage inflammatory protein 1-beta antibody
      • Macrophage inflammatory protein 1b2 antibody
      • MGC104418 antibody
      • MGC126025 antibody
      • MGC126026 antibody
      • MIP-1-beta antibody
      • MIP-1-beta(1-69) antibody
      • MIP-1-beta(3-69) antibody
      • MIP1 beta antibody
      • MIP1B antibody
      • MIP1B1 antibody
      • Monocyte adherence induced protein 5 alpha antibody
      • PAT 744 antibody
      • Protein H400 antibody
      • SCYA2 antibody
      • SCYA4 antibody
      • SCYA4L antibody
      • SCYA4L1 antibody
      • SCYA4L2 antibody
      • SCYQ4L2 antibody
      • Secreted protein G 26 antibody
      • Secreted protein G26 antibody
      • SIS gamma antibody
      • SIS-gamma antibody
      • Small inducible cytokine A4 (homologous to mouse Mip 1b) antibody
      • Small inducible cytokine A4 antibody
      • small inducible cytokine A4-like antibody
      • Small-inducible cytokine A4 antibody
      • T cell activation protein 2 antibody
      • T-cell activation protein 2 antibody
      see all

    References

    ab84439 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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