You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Macrophage Inflammatory Protein 3 beta (Active) (ab9832)

Submit an Abreview Submit a Question

Overview

  • Product nameMacrophage Inflammatory Protein 3 beta (Active)See all Macrophage Inflammatory Protein 3 beta proteins and peptides ...
  • Protein descriptionHighly pure (>98%) recombinant human Macrophage Inflammatory Protein 3 beta.
  • Expression hostE. coli

    • Properties

  • Purification notesSterile filtered Greater than 99% pure by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • FormLyophilised
  • Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.This product is an active protein and may elicit a biological response in vivo, handle with caution.
  • Concentration information loading...
  • Additional notesThe biological activity of this product was determined by its ability to chemoattract human T cells using a concentration of 10.0-50.0 ng/ml.
  • Sequence notesHuman MIP-3-beta is an 8.8 kDa protein containing 77 amino acid residues: GTNDAEDCCL SVTQKPIPGY IVRNFHYLLI KDGCRVPAVV FTTLRGRQLC APPDQPWVER IIQRLQRTSA KMKRRSS
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab9832 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.
    Functional Studies FuncS: Use at an assay dependent dilution.
  • Application notesThis peptide can be used with studies using ab9351 and ab9831.

    • Protein info

    • Alternative names
        Beta chemokine exodus 3Beta-chemokine exodus-3C C chemokine ligand 19
        C-C motif chemokine 19CC chemokine ligand 19CCL 19CCL19CCL19_HUMANChemokine (C C motif) ligand 19Chemokine (CC motif) ligand 19Chemokine C C Motif Ligand 19Chemokine CC Motif Ligand 19CK beta 11CK beta-11CKb 11CKb11EBI 1 ligand chemokineEBI1 ligand chemokineELCEpstein-Barr virus-induced molecule 1 ligand chemokineExodus 3Exodus3Macrophage inflammatory protein 3 betaMGC34433MIP 3 betaMIP 3BMIP-3-betaMIP3 betaMIP3BOTTHUMP00000000531SCYA 19SCYA19Small inducible cytokine A19Small inducible cytokine subfamily A (Cys Cys) member 1Small-inducible cytokine A19
      see all
  • FunctionMay play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Specifically binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes.
  • Tissue specificityExpressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach.
  • Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.
  • Cellular localizationSecreted.

    • Target information above from: UniProt accession Q99731 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for Macrophage Inflammatory Protein 3 beta (Active) (ab9832)

    ab9832 has not yet been referenced specifically in any publications.

    Publishing research using ab9832 ? Please let us know so that we can cite the reference in this datasheet

    Product Wall

    Submit an Abreview for ab9832 Submit a Question for ab9832

    There are currently no Abreviews or Questions for ab9832.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"