Anti-Macrophage Inflammatory Protein 3 beta antibody (ab9831)

Overview

  • Product nameAnti-Macrophage Inflammatory Protein 3 beta antibody
    See all Macrophage Inflammatory Protein 3 beta primary antibodies
  • Description
    Rabbit polyclonal to Macrophage Inflammatory Protein 3 beta
  • Tested applicationsSuitable for: WB, ELISA, Neutralisingmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Highly pure (>98%) recombinant hMIP-3-b (human macrophage inflammatory protein-3 beta)

Properties

Applications

Our Abpromise guarantee covers the use of ab9831 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. To detect hMIP-3-b by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 µg/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hMIP-3-b is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
ELISA Use at an assay dependent concentration. To detect hMIP-3-b by direct ELISA (using 100µl/well antibody solution) a concentration of at least 0.5µg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of 0.2 - 0.4 ng/well of recombinant hMIP-3-b.
Neutralising Use at an assay dependent concentration. To yield one-half maximal inhibition [ND50] of the biological activity of hMIP-3-b (100 ng/ml), a concentration of 2.7 - 4.0 µg/ml of this antibody is required.

Target

  • FunctionMay play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Specifically binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes.
  • Tissue specificityExpressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach.
  • Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Beta chemokine exodus 3 antibody
    • Beta-chemokine exodus-3 antibody
    • C C chemokine ligand 19 antibody
    • C-C motif chemokine 19 antibody
    • CC chemokine ligand 19 antibody
    • CCL 19 antibody
    • CCL19 antibody
    • CCL19_HUMAN antibody
    • Chemokine (C C motif) ligand 19 antibody
    • Chemokine (CC motif) ligand 19 antibody
    • Chemokine C C Motif Ligand 19 antibody
    • Chemokine CC Motif Ligand 19 antibody
    • CK beta 11 antibody
    • CK beta-11 antibody
    • CKb 11 antibody
    • CKb11 antibody
    • EBI 1 ligand chemokine antibody
    • EBI1 ligand chemokine antibody
    • ELC antibody
    • Epstein-Barr virus-induced molecule 1 ligand chemokine antibody
    • Exodus 3 antibody
    • Exodus3 antibody
    • Macrophage inflammatory protein 3 beta antibody
    • MGC34433 antibody
    • MIP 3 beta antibody
    • MIP 3B antibody
    • MIP-3-beta antibody
    • MIP-3b antibody
    • MIP3 beta antibody
    • MIP3B antibody
    • OTTHUMP00000000531 antibody
    • SCYA 19 antibody
    • SCYA19 antibody
    • Small inducible cytokine A19 antibody
    • Small inducible cytokine subfamily A (Cys Cys) member 1 antibody
    • Small-inducible cytokine A19 antibody
    see all

References for Anti-Macrophage Inflammatory Protein 3 beta antibody (ab9831)

ab9831 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"